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NHLBI-PEN Publications, Presentations and Patents

Publications:

  1. Huafeng Fang; Xuan Yue; Xiaoxu Li; John-Stephen Taylor. 'Identification and characterization of high affinity antisense PNAs for the human unr (upstream of N-ras) mRNA which is uniquely overexpressed in MCF-7 breast cancer cells', Nucleic Acids Res. 2005, 33, 6700-6711.
  2. Lee, Cameron C.; MacKay, John A.; Fréchet, Jean M. J.; Szoka, Francis C. 'Designing dendrimers for biological applications', Nature Biotechnology 2005, 23(12), 1517-1526.
  3. Kwon, Young Jik; James, Edward; Shastri, Nilabh; Fréchet, Jean M. J.  'In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles'. Proc. Nat. Acad. Sci., 2005, 102(51), 18264-18268.
  4. Wu, P.; Malkoch, M.; Hunt, J.N.; Vestberg, R.; Kaltgrad, E.; Finn, M.G.; Fokin V.V.; Sharpless, K.B.; Hawker, C.J. 'Multivalent, bifunctional dendrimers prepared by click chemistry.' Chem. Comm. 2005, 5775-5777.
  5. Goodwin, Andrew P.; Mynar, Justin L.; Ma, Yingzhong; Fleming, Graham R.; Fréchet, Jean M. J. 'Strategy for two-photon light sensitive polymeric micelle design'. Polym. Mat. Sci. Eng., 2006, 94, 131-132.
  6. Mynar, Justin L.; Lowery, Thomas J.; Wemmer, David E.; Pines, Alexander; Fréchet, Jean M. J.. 'Xenon Biosensor Amplification via Dendrimer-Cage Supramolecular Constructs.' Journal of the American Chemical Society 2006, 128(19), 6334-6335.
  7. Fukukawa, K.; Pressly, E.D.; Gupta, N.; Hawker, C.J. 'Synthesis of pegylated star microgel with core functionality for click chemistry by nitroxide-mediated radical polymerization.' Polymer Preprints (American Chemical Society, Division of Polymer Chemistry) 2006, 47(1), 466-467.
  8. O Reilly, R.; Joralemon, M. J.; Hawker, C. J.; Wooley, K. L. 'Fluorogenic 1,3-Dipolar Cycloaddition within the Hydro phobic Core of a Shell Cross-Linked Nanoparticle' J. Polym. Sci., Part A: Polym. Chem. 2006, 44(17), 5203-5217.
  9. Li, Y.; Harrisson, S.; Wooley, K. L. 'Shell Crosslinked Nanoparticles Containing Degradable Crosslinkers for Controlled Drug Delivery' Polym. Prepr. 2006, 47(2), 147.
  10. Messmore, B.W.; Fukukawa, Ken-ichi; Pressly, E.D.; Hawker, C.J. 'Poly(ethylene glycol) containing nanostructures with medical imaging applications.' Polymer Preprints (American Chemical Society, Division of Polymer Chemistry) 2006, 47(2), 415-416.
  11. R. Rossin, E. Pressly, K. Fukukawa, B. Messmore, J.L. Turner, M.J. Joralemon, M.L. Becker, C. Hawker, K.L. Wooley, M.J. Welch. 'Evaluation of 64Cu-radiolabeled nanoparticles for the diagnosis and treatment of disease' in Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine 7 U. Mazzi (ed.), Proc. of the 7th International Symposium on Technetium in Chemistry and Nuclear Medicine, 2006.
  12. Standley, S. M.; Mende, I.; Goh, S. L.; Kwon, Y. J.; Beaudette, T. T.; Engelman, E. G.; Fréchet, J. M. J. 'Incorporation of CpG Oligonucleotide Ligand into Protein-Loaded Particle Vaccines Promotes Antigen-Specific CD8 T-Cell Immunity' in Bioconj. Chem., 2007, 18(1), 77-83.
  13. Jain, R.; Standley, S. M.; Fréchet, J. M. J. 'Synthesis and Degradation of pH-Sensitive Linear poly(amidoamine)s' in Macromolecules, 2007, 40(3), 452-457.
  14. Lee, C. C.; Gillies, E. R.; Fox, M. E.; Guillaudeu, S. J.; Fréchet, J. M. J.; Dy, E. E.; Szoka, F. C. 'A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas' in Proc. Nat. Acad. Sci.. 2006, 103, 16649-54.
  15. Lee, C. C.; Cramer, A. T.; Szoka, F. C.; Fréchet, J. M. J. 'An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin' in Bioconjugate Chemistry., 2006, 17, 1364-13685.
  16. Lee, C. C.; Fréchet, J. M. J. 'Synthesis and conformation of dendronized poly(L-lysine)' in Macromolecules, 2006, 39, 476-48.
  17. Venkataraman, S.; Wooley, K. L. 'ATRP from an Amino Acid-Based Initiator: A Facile Approach for Functionalized Polymers' in Macromolecules. 2006, 39(26), 9661-9664.
  18. O’Reilly, R. K.; Joralemon, M. J.; Hawker, C. J.; Wooley, K. L. 'Facile Syntheses of Surface-functionalized Micelles and Shell Cross-linked Nanoparticles' in J. Polym. Sci., Part A: Polym. Chem. 2006, 44, 5203-5217.
  19. Sun, G.; Cheng, C.; Wooley, K. L. 'Reversible Addition Fragmentation Chain Transfer (RAFT) Polymerization of 4-Vinylbenzaldehyde' in Macromolecules, 2007, 40(4) 793-795.
  20. Van Horn, B. A.; Wooley, K. L. 'Toward Crosslinked Degradable Polyester Materials: Investigations into the compatibility and use of reductive amination chemistry for crosslinking' in Macromolecules, 2007, 40(5) 1480-1488.
  21. O’Reilly, R. K.; Joralemon, M. J., Hawker, C. J.; Wooley, K. L. 'Preparation of Orthogonally-functionalized Core Click Cross-linked Nanoparticles', New J. Chem., 2007, 31(5) 718-724.
  22. Powell, K. T.; Cheng, C.; Wooley, K. L. 'Complex Amphiphilic Hyperbranched Fluoropolymers by Atom Transfer Radical Self-condensing Vinyl Copolymerization', Macromolecules, 2007, 40(13) 4509-4515.
  23. Xu, J.; Sun, G.; Rossin, R.; Hagooly, A.; Li, Z.; Fukukawa, K.; Messmore, B. W.; Moore, D. A.; Welch, M. J.; Hawker, C. J.; Wooley, K. L. 'Labeling of Polymer Nanostructures for Medical Imaging: Importance of charge density, spacer length, and crosslinking extents', Macromolecules, 2007, 40(9) 2971-2973.
  24. Mynar, J.L.; Goodwin, A.P.; Cohen, J.A.; Ma, Y.; Fleming, G.R.; Fréchet, J.M.J. 'Two-photon degradable supramolecular assemblies of linear-dendritic copolymers.', Chemical Communications, 2007, (20), 2081-2082.
  25. Berezin, M. Y.; Lee, H.; Akers, W.; Nikiforovich, G.; Achilefu, S. 'Ratiometric Analysis of Fluorescence Lifetime for Probing Binding Sites in Albumin with Near Infrared Fluorescent Molecular Probes.' Photochem. Photobiol., 2007, 83, 1-8.
  26. Berezin, M. Y.; Lee, H.; Akers, W.; Achilefu, S. 'Near infrared dyes as lifetime solvatochromic probes for micropolarity measurements of biological systems', Biophys J 2007, 93 (8), 2892-9.
  27. Bartels, J.W; Cheng, C.; Powell, K.T.; Xu, J.; Wooley, K.L. 'Hyperbranched Fluoropolymers and their Hybridization into Complex Amphiphilic Crosslinked Copolymer Networks', Macromolecular Chemistry and Physics, 2007, 208(15), 1676-1687.
  28. Sun, G.; Xu, J.; Hagooly, A.; Rossin, R.; Li, Z.; Moore, D.A.; Welch, M.J.; Wooley, K.L. 'Strategies for Optimized Radiolabeling of Nanoparticles for in vivo MicroPET Imaging;', Advanced Materials (Weinheim, Germany), 2007, 19(20), 3157-3162.
  29. Goodwin, A.P., Lam, S.S., Fréchet, J.M.J. 'Rapid, Efficient Synthesis of Heterobifunctional Biodegradable Dendrimers', Journal of American Chemical Society, 2007, 129(22), 6994-6995.
  30. Pressly, E. D.; Rossin, R.; Hagooly, A.; Fukukawa, K.; Messmore, B. W.; Wooley, K. L.; Welch, M. J.; Lamm, M.; Hule, R.; Pochan, D. J.; Hawker, C. J., 'Rapid Structural Effects on the Biodistribution and Positron Emission Tomography (PET) Imaging of Well-defined 64Cu-Labeled Nanoparticles Comprised of Amphiphilic Block Graft Copolymers', Biomacromolecules, 2007, 8, 3126-3134.
  31. Li, Y.; Sun, G.; Xu, J.; Wooley, K. L. ; 'Shell Crosslinked Nanoparticles: A progress report of their design for drug delivery', a chapter in the book 'Nanotechnology in Therapeutics: Current technology and applications' J. Zach Hilt, J. Brock Thomas and Nicholas A. Peppas editors, Horizon Bioscience, Wymondham, UK, 2007, 381-407, ISBN-13: 978-1-904933-29-8.
  32. Chen, Z.; Cheng, C.; Germack, D. S.; Gopalan, P.; Van Horn, B. A.; Venkataraman, S.; Wooley, K. L.; 'Complex Functional Macromolecules' Chapter 18 of Volume 2: 'Elements of Macromolecular Structural Control' within the book series 'Macromolecular Engineering', edited by K. Matyjaszewski, Y. Gnanou, and L. Leibler, Wiley-VCH, Weinheim, 2007, 2, 1341-1385, ISBN-13: 978-3-527-31446-1.
  33. Cheng, C.; Powell, K.T.; Khoshdel, E.; Wooley, K. L.; 'Polydimethylsiloxane- (PDMS-) Grafted Fluorocopolymers by a "Grafting through" Strategy Based on Atom Transfer Radical (Co)polymerization', Macromolecules; (Article); 2007, 40(20), 7195-7207.
  34. Cheng, C.; Sun, G.; Khoshdel, E.; Wooley, K.L. 'Well-Defined Vinyl Ketone-Based Polymers by Reversible Addition-Fragmentation Chain Transfer Polymerization', J. Am. Chem. Soc., 2007, 129(33) 10086-10087.
  35. Li, Y.; Du, W.; Sun, G.; Wooley, K.L. 'Preparation of Shell Crosslinked Nanoparticles Containing pH Sensitive Crosslinkers for Drug Delivery', PMSE Preprints, 2007, 97, 322.
  36. Schuster, D.P. 'The opportunities and challenges of developing imaging biomarkers to study lung function and disease', American journal of respiratory and critical care medicine, 2007, 176(3), 224-30.
  37. Connal, L. A.; Vestberg, R.; Hawker, C.J.; Qiao, G.G. 'Synthesis of Dendron Functionalized Core Cross-linked Star Polymers', Macromolecules, 2007, 40(22), 7855-7863.
  38. An, Z.; Shi, Q.; Tang, W.; Tsung, C.K.; Hawker, C.J.; Stucky, G.D. 'Facile RAFT Precipitation Polymerization for the Microwave Assisted Synthesis of Well-Defined, Double Hydrophilic Block Copolymers and Nanostructured Hydrogels', J. Am. Chem. Soc, 2007, 129(46), 14493-14499.
  39. Li, Y.; Akiba, I.; Harrisson, S.; Wooley, K.L. 'Facile Formation of Uniform Shell Crosslinked Nanoparticles with Built-in Functionalities from N-hydroxysuccinimide-activated Amphiphilic Block Copolymers', Adv. Func. Mater., 2007, 18, 551-559.
  40. Oquare, B. Y., Fang, H. & Taylor, J.-S. 'Peptide nucleic acid (PNA) FRET agents for imaging gene expression', Abstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, August 19-23, 2007, MEDI-104.
  41. Fang, H., Oquare, B. Y., Zhang, Y. & Taylor, J.-S.  'Antisense cassette for gene expression imaging'. Abstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, August 19-23, 2007, BIOL-168.
  42. Kshetry, A. & Taylor, J. S.  'Synthesis of orthogonally protected peptide nucleic acid (PNA) building block for attachment of groups to C5 of U'. Abstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, August 19-23, 2007, ORGN-142.
  43. Lee, N.S., Li, Y., Ruda, C. M., Wooley, K.L., 'Aqueous-only pH-induced micelle assembly of poly(acrylic acid)-b-poly(p-hydroxystyrene),' Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 2007, 48(1), 866.
  44. Cohen, J.L., Almutairi, A., Cohen, J.A., Schuster, D., Fréchet, J.M.J.  “Enhanced cell penetration of acid degradable particles functionalized with cell penetrating peptides.” Bioconjugate Chemistry, 2008, 19(4), 876-881.
  45. Almutairi, A., Berezin, M.Y., Guillaudeu, S., Achilefu, S., Fréchet, J.M.J. (2007) “Biodegradable pH sensing dendritic nanoprobes for near infrared fluorescence lifetime and intensity imaging.” Journal of the American Chemical Society, 2008, 130(2), 444-445.
  46. Zheng J., Ochoa E., Misselwitz B., Yang D., El Naqa I., Woodard P.K., Abendschein D. 'Targeted contrast agent helps to monitor advanced plaque during progression: A magnetic resonance imaging study in rabbits', Invest Radiol., 2008 Jan, 43(1):49-55.
  47. McCommis K.S., Rossin R., Abendschein D.R., Ochoa B., Woodard G.E., Welch M.J., Woodard P.K., Zheng J. Detection of atherosclerotic plaque progression: Correlation of contrast MRI with PET using 64Cu-labeled natriuretic peptide. [submitted to Proceedings of the International Society of Magnetic Resonance in Medicine Annual Meeting], 2008.
  48. Berezin, M., Lee, H., Akers, W., Nikiforovich, G., Achilefu, S., 'Fluorescent lifetime of near infrared dyes for structural analysis of serum albumin', Proc. SPIE, 2008, 6867, Molecular Probes for Biomedical Applications II, 68670J/1-68670J/11.
  49. Takizawa, K.; Nulwala, H.; Thibault, R. J.; Lowenhielm, P.; Wooley, K. L.; Hawker, C. J. “Facile Routes for the Syntheses of 4-Vinyl-1,2,3-Triazole Monomers by Click Azide/Acetylene Coupling”, J. Polym. Sci., Part A: Polym. Chem., 2008, 46(9), 2897-2912.
  50. Van Horn, B. A.; Iha, R. K.; Wooley, K. L. “Sequential and single-step, one-pot strategies for the transformation of hydrolytically-degradable polyesters into multi-functional systems”, Macromolecules, 2008, 41(5), 1618-1626.
  51. Zhou, C.; Qi, K.; Wooley, K. L.; Walker, A. V. 'Time-of-flight secondary ion mass spectrometry, fluorescence microscopy and scanning electron microscopy: Combined tools for monitoring the process of patterning and layer-by-layer assembly of synthetic and biological materials', Colloids and Surfaces B, Biointerfaces, 2008,  65(1), 85-91.
  52. Fukukawa, K.; Rossin, R.; Hagooly, A.; Pressly, E. D.; Hunt, J. N.; Messmore, B. W.; Wooley, K. L.; Welch, M. J.; Hawker, C. J., 'Synthesis and characterization of core-shell star copolymers for in vivo PET imaging applications', Biomacromolecules, 2008, 9(4),  1329-1339.
  53. Ma, J.; Cheng, C.; Sun, G.; Wooley, K. L. 'A polarity-activation strategy for the high incorporation of 1-alkenes into functional copolymers via RAFT copolymerization', J. Am. Chem. Soc., submitted.
  54. Nyström, A. M.; Wooley, K. L. 'Construction of thermoresponsive SCKs through tuning the crystalline melting point of the core domain', Soft Matter, 2008, 4(4), 849-858.
  55. Sun, G.; Hagooly, A.; Xu, J.; Nyström, A. M.; Li, Z.; Rossin, R.; Moore, D. A.; Wooley, K. L.; Welch, M. J. 'Facile, Efficient Approach to Accomplish Tunable Chemistries and Variable Biodistributions for Shell Cross-Linked Nanoparticles', Biomacromolecules, 2008, ASAP.
  56. Rossin, R.; Muro, S.; Welch, M. J.; Muzykantov, V.R.; Schuster, D.P., 'In vivo imaging of 64Cu-labeled polymer nanoparticles targeted to the lung endothelium', J Nucl Med, 2008, 49(1), 103-11.
  57. Li, Y.; Du, W.; Sun, G.; Wooley, K. L.  "pH-Responsive Shell Crosslilnked Nanoparticles with Hydrolytically-labile Crosslinks", submitted to J. Am. Chem Soc., 2008.
  58. Powell, K. T., Shokeen, M., Anderson, C. J., Wooley, K. L.  "Nanomedicine as a Special Topics Course in Organic Chemistry:  A template for applying cyber infrastructure within the post-secondary classroom", Journal of Chemistry Education, 2008, submitted.
  59. Nyström, A. M., Xu, Z., Xu, J., Taylor, S., Nittis, T., Stewart, S. A., Leonard, J., Wooley, K. L.  "SCKs as nanoparticle carriers of doxorubicin:  investigation of core composition on the loading, release and cytotoxicity profiles", Chem. Commun., 2008, ASAP.
  60. Nyström, A. M., Wooley, K. L.  "Thiol-functionalized shell crosslinked knedel-like (SCK) nanoparticles:  a versatile entry for their conjugation with biomacromolecules", Tetrahedron, 2008, ASAP.
  61. Du, W., Nyström, A. M., Lei, Z., Powell, K. T., Li, Y. Cheng, C., Wickline, S. A., Wooley, K. L.  "Amphiphilic Hyperbranched Fluoropolymers as Nanoscopic 19F-Magnetic Resonance Imaging Agent Assemblies", Biomacromolecules, 2008, submitted.
  62. Lee, N. S., Neumann, W. L., Freskos, J. N., Marzan, T. A., Shieh, J. J., Dorshow, R. B., Wooley, K. L., "Photonic shell-crosslinked nanoparticle probes for optical imaging and monitoring."  Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 2008, 49(1), 1052.
  63. Lee, N. S., Neumann, W. L., Freskos, J. N., Marzan, T. A., Shieh, J. J., Dorshow, R. B., Wooley, K. L., "Photonic shell-crosslinked nanoparticle probes for optical imaging and monitoring," 2008, BIOMED-Optical Society of America.
  64. Akers, W., Berezin, M., Lee, H., Achilefu S. Predicting In Vivo Fluorescence Lifetime Behavior of NIR Fluorescent Contrast Agents Using In Vitro Measurements, J. Biomed. Opt. 2008 (accepted) 

  65. Shokeen M; Fettig N M; Rossin R   Synthesis, in vitro and in vivo evaluation of radiolabeled nanoparticles.    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology  (2008),  52(3),  267-77.  Journal code: 101213861.  ISSN:1824-4785.  PubMed ID 18475250 AN 2008380354    In-process for MEDLINE

  66. Almutairi, A., Rossin R., Shokeen, M., Guillaudeu, S., Abendschein, D., Anderson C. J., Welch, M., Fréchet, J. M. J., "Biodegradable multivalent positron emitting nanoprobes highly selective for overexpression of αvβ3 integrin for non invasive imaging of angiogenesis", PNAS, (Manuscript in preparation, 2008)
     

Presentations:

  1. Goodwin, A., Mynar, J.L., Ma, Y., Fleming, G.R., Fréchet, J.M.J. "Polymer Amphiphiles Sensitive to Two-Photon Near IR Irradiation", 231st American Chemical Society Meeting, Atlanta, GA., March 28, 2006.
  2. Fukukawa, K., Pressly, E., Gupta, N., Hawker, C. J. "Synthesis of PEGylated star microgel with core functionality for click chemistry by nitroxide-mediated radical polymerization", 231st American Chemical Society Meeting, Atlanta, GA, March 28, 2006, POLY-300.
  3. Li, Y., Harrisson, S., Wooley, K. L., "Biodegradable Nanoparticles for Drug Delivery", Graduate Student Research Symposium, St. Louis, MO, April, 1, 2006.
  4. R. Rossin, X. Sun, J.-S. Taylor, K.L. Wooley, M.J. Welch.  "Evaluation of 64Cu-Radiolabeled Targeted Nanoparticles for the Diagnosis and Treatment of Disease, Nanotechnologies and the Life Sciences", Burnham Institute 28th Annual Symposium, La Jolla, CA, 13-14 April 2006.
  5. Li, Y., Harrisson, S., Wooley, K. L., "Biodegradable Nanoparticles for Drug Delivery", 19th Missouri Organic Chemistry Day, Columbia, MO, April, 29, 2006.
  6. Fukukawa, K., Pressly, E., Gupta, N., Hawker, Craig J. "Synthesis of PEGylated star microgel with core functionality for click chemistry by nitroxide-mediated radical polymerization", CNST Nanotechnology Workshop, Urbana-Champaign, IL, May 4-5, 2006.
  7. Berezin, M., Akers, W., Bloch, S., Achilefu, S., "Roles of nanomolecules and nanomaterials in optical imaging of tumors in-vivo", CNST Nanotechnology Workshop, Urbana-Champaign, IL, May 4-5, 2006.
  8. M. Berezin, S. Bloch, Akers, W.,  Ye, Y., Liang, K., Achilefu,S., "Fluorescent nanosized and organic probes in optical imaging of tumors", CNST Nanotechnology Workshop, Urbana-Champaign, IL, May 4-5, 2006.
  9. De Leo, G., Wooley, K.L., Hawker, C.J., Fréchet, J.M.J, Welch, M.J., Schuster, D.P, Anderson, C.J.,  "Integrated Nanosystems for Diagnosis and Therapy NHLBI Program of Excellence in Nanotechnology", CNST Nanotechnology Workshop, Urbana-Champaign, IL, May 4-5, 2006.
  10. Wooley, K.L., "The Development of Shell Crosslinked Nanoparticles for Biomedical Applications in vivo", Kodak Emerging Technologies Symposium, Eastman Kodak Company, Rochester, NY, May 12, 2006.
  11. Almutairi, A. and Fréchet, J.M.J "Polymer based nano-systems for combined diagnosis and therapy", 12th International Conference on Polymers and Organic Chemistry, Okazaki, Japan. July 2-7, 2006.
  12. Almutairi, A. Akers, W., Abendschein, D., Berezin, M., Achilefu, S., Fréchet, J.M.J. "Polymer based nano-systems for combined diagnosis and therapy", Gordon Research Conference, Big Sky, Montana, September 3-8, 2006.
  13. Cohen, J. A., Akers, W., Berezin, M., Achilefu, S.A., Fréchet, J.M.J. "Poly(acrylamide)-based microparticles for cardiovascular imaging and therapeutic applications", Fall American Chemical Society Meeting, San Francisco, CA, September 10-14, 2006.
  14. Almutairi, A., Akers, W., Abendschein, D., Berezin, M., Achilefu, S.A., Fréchet, J.M.J. "Dendrimer-polymer based nano-systems for combined diagnosis and therapy", Fall American Chemical Society Meeting, San Francisco, CA, September 10-14, 2006.
  15. Li, Y., Harrisson, S., Wooley, K.L. "Shell Crosslinked Nanoparticles Containing Degradable Crosslinkers for Controlled Drug Delivery", 232nd National American Chemical Society Meeting, San Francisco, CA, September 10-14, 2006.
  16. Oquare, B.Y., Fang, H. and Taylor, J.S. "Design and synthesis of peptide nucleic acid (PNA) FRET and probes and molecular beacons (MBs) or mRNA targeting and direct imaging of gene transcription", Abstracts of Papers, 232nd National American Chemical Society Meeting, San Francisco, CA, United States, Sept. 10-14, 2006, BIOL-106.
  17. Goodwin, E. R., Lee, C. C., Fox, M. E., Fréchet, J.M.J. "Synthetic variability in asymmetric dendrimers for drug delivery", 232nd Fall American Chemical Society Meeting,San Francisco, CA, USA. (Oral Presentation) 2006.
  18. Almutairi, A., Akers, W., Abendschein, D., Berezin, M., Achilefu, S. A., Fréchet, J.M.J., "Dendrimer-polymer based nano-systems for combined diagnosis and therapy", 232nd Fall American Chemical Society Meeting, San Francisco, CA, USA. (Oral Presentation), 2006.
  19. Cohen, J. A., Akers, W., Berezin, M., Achilefu, S. A., Fréchet, J.M.J. "Poly(acrylamide)-based microparticles for cardiovascular imaging and therapeutic applications", 232nd Fall American Chemical Society Meeting, San Francisco, CA, USA. (Poster Presentation), 2006.
  20. R. Rossin, E. Pressly, et al. "Evaluation of 64Cu-radiolabeled nanoparticles for the diagnosis and treatment of disease", 7th International Symposium on Technetium in Chemistry and Nuclear Medicine, Bressanone (BZ) - Italy, Sept. 6-9. (Poster Presentation), 2006.
  21. Wooley, K.L. "Well-defined Nanostructured Materials: Discrete nanoobjects and nanoscopically-resolved crosslinked networks, and study of their unique host behaviors", University of Utah, Department of Chemistry, Salt Lake City, UT, February 2, 2006.
  22. Wooley, K.L. "Well-defined Nanostructured Materials: Discrete nanoobjects and nanoscopically-resolved crosslinked networks, and study of their unique host behaviors", William H. Rauscher Lectureship, Rennselaer Polytechnic Institute, Department of Chemistry, Troy, NY, February 14, 2006.
  23. Wooley, K.L. "Well-defined Nanostructured Materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", Purdue University, Weldon School of Biomedical Engineering, West Lafayette, IN, March 1, 2006.
  24. Wooley, K.L. "Well defined nanostructured materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", New York University, Department of Chemistry, New York, NY, April 14, 2006.
  25. Wooley, K.L. "Well defined nanostructured materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", University of Florida, Department of Chemistry and Center for Macromolecular Science & Engineering, Gainesville, FL, April 20, 2006.
  26. Wooley, K.L. "Well defined nanostructured materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", University of Delaware, Department of Materials Science and Engineering, Newark, DE, May 3, 2006.
  27. Wooley, K.L. "Well defined nanostructured materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks…and study of their unique host behaviors", University of Massachusetts, Department of Chemistry, Amherst, MA, May 11, 2006.
  28. Wooley, K.L. "The Development of Shell Crosslinked Nanoparticles for Biomedical Applications in vivo", Kodak Emerging Technologies Symposium, Eastman Kodak Company, Rochester, NY, May 12, 2006.
  29. Wooley, K.L. "The Syntheses and Studies of Nanoscale Polymer-based Objects Originating from Block Copolymer Self Assembly, Brush Block Copolymer Construction, or Cellulose Nanocrystal Templating", Unilever Research China, Shanghai, China, June 7, 2006.
  30. Wooley, K.L. "Well-defined Nanostructures Facilitated by Living Polymerization and Supramolecular Assembly", Macro Group UK International Conference on Polymer Synthesis, University of Warwick, UK, July 31, 2006.
  31. Wooley, K.L. "The Transformation of Block Copolymers into Discrete Nanoscale Objects and into Bulk Composite Materials that Present Complex Features", Mitsubishi Chemical Corporation Technical Advisory Board on Polymer Nanocomposites, Tokyo, Japan, August 30-September 1, 2006.
  32. Wooley, K.L. "The Development of Shell Crosslinked Nanoparticles for Biomedical Applications in vivo", 2nd International Conference on Bioengineering and Nanotechnology, Santa Barbara, CA, September 5-7, 2006.
  33. Wooley, K.L. "Shaped Core-shell Morphologies Assembled Intramolecularly within Brush Block Copolymers and Intermolecularly between Linear Block Copolymers", 232nd American Chemicial Society National Meeting, San Francisco, CA, September 10, 2006.
  34. Wooley, K.L. "The Development of Shell Crosslinked Nanoparticles for Biomedical Applications in vivo", 232nd American Chemical Society National Meeting, San Francisco, CA, September 10, 2006.
  35. Wooley, K.L. "Well Defined Nanostructured Materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", Indiana University, Department of Chemistry, Bloomington, IN, October 4, 2006.
  36. Wooley, K.L. "Well Defined Nanostructured Materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", 2006 Xerox Distinguished Lecture Series, Mississauga, ON, Canada, October 20, 2006.
  37. Wooley, K.L. "The Transformation of Block Copolymers into Discrete Nanoscale Objects and into Bulk Composite Materials that Present Complex Features, Each with Consideration of Biomedical Applications", University of Missouri-Kansas City, Department of Chemistry, Kansas City, MO, November 2, 2006.
  38. Wooley, K.L. "The Development of Well-defined Nanoscale Objects for Biomedical Applications (with tissue selective targeting) in vivo", American Heart Association Scientific Sessions 2006, Chicago, IL, November 12, 2006.
  39. Wooley, K.L. "Shell crosslinked block copolymer micelles: Robust nanostructured materials for fundamental studies and applications in nanomedicine", Center for Drug Delivery and Nanomedicine, University of Nebraska Medical Center, College of Pharmacy, Omaha, NE, November 16, 2006.
  40. Wooley, K.L. "The Transformation of Block Copolymers into Bulk Composite Materials that Present Complex Features and into Discrete Nanoscale Objects", Northwestern University, Department of Chemistry, Evanston, IL, November 17, 2006.
  41. Wooley, K.L. "Complex, amphiphilic polymer nanostructures, originating from combinations of living polymerizations, supramolecular assembly and regioselective crosslinking", Columbia University, Department of Chemistry, New York, NY, February 1, 2007.
  42. Wooley, K.L. "The Promise of Nanotechnology in Medicine", Frontiers in Human Pathobiology Seminar Series, Washington University School of Medicine, St. Louis, MO, February 14, 2007.
  43. Wooley, K.L. "Organic Nanostructures with Well-defined Size, Shape, Structure and Properties", University of Illinois, Urbana-Champaign, Chemistry-Biology Interface Seminar, Urbana, IL, March 12, 2007.
  44. Wooley, K.L. "Complex Constructs Having Nanoscale Features by Combining Incompatible Polymer Components", 233rd American Chemical Society National Meeting, Chicago, IL, March 25 2007.
  45. Wooley, K.L. "Nanoparticles and Nanocages Originating from Well-defined Brush Block Copolymers", 233rd American Chemical Society National Meeting, Chicago, IL, March 28, 2007.
  46. Xu, J., Wooley, K. L. "Functionalization of shell crosslinked nanoparticles and their biodistribution assessment", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  47. Venkataraman, S., Wooley, K. L. "Polymerization of di(ethylene glycol) 2-ethyl hexyl ether acrylate via reversible addition-fragmentation chain transfer polymerization", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  48. Venkataraman, S., Wooley, K. L. "Importance of the hydrophobic core of nanostructures prepared from amphiphilic block copolymers to the morphology of calcium carbonate crystals", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  49. Shokeen M., Powell K. T., Anderson, C. J., Wooley, K. L. "Taking the graduate classroom teaching a step further", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  50. Lee, N., Ruda, M.C., Li, Y., Wooley, K.L. "Aqueous-only pH induced micelle assembly of poly(acrylic acid)-b-poly(p-hydroxystyrene)", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  51. Powell, K.T., Cheng, C., Du, W., Wooley, K.L. "Hyperbranched Fluorobranched (HBFP(III)) Designed as Complex Nanostructures for Potential Imaging and Therapeutic Delivery", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  52. Almutairi, A., Cohen, J. A., Akers, W., Achilefu, S., Fréchet, J.M.J. "Polymer based nano-systems for combined diagnosis and therapy", Gordon Research Conference, Ventura, CA, USA 2007.
  53. Almutairi, A., Cohen, J. A., Akers, W., Achilefu, S., Fréchet, J.M.J. "Polymer based nano-systems for combined diagnosis and therapy", Gordon Research Conference, Ventura, CA, USA. (Poster Presentation) 2007.
  54. Almutairi, A. 'Designing Nanoscale Delivery Vehicles for Bioactive Agents", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  55. Rossin, R. "Nanotechnology for Imaging and Imaging for Nanotechnology: In vivo evaluation of new radiolabeled stealth nanocarriers", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  56. Taylor, J.S. "PNA-based Agents for Imaging Gene Expression", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  57. Fiamengo, A.L., Shokeen, M., Li, Z., Sun, G., Xu, Z., Pressly, E., Hawker, C., Wooley, K.L. and Anderson, C.J., "Binding affinity determination of RGD-functionalized nanoparticles to αvβ3 and αvβ5 integrins", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  58. Xu, J., Sun, G., Hagooly, A., Rossin, R., Li, Z., Fukukawa, K., Messmore, B., Moore, D., Welch, M.J., Hawker, C. and Wooley, K.L. "Functionalization of Shell Crosslinked Nanoparticles and Their Biodistribution Assessment", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  59. Du, W., Powell, K.T., Zheng, J., Conradi, M., Wooley, K.L. "Unique Nanostructures through PEGylation of Hyperbranched Fluoropolymer (HBFP) Scaffolds", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  60. Li, Y., Nyström, A.M., Wooley, K.L. "Hydrolytically-degradable nanoparticles for drug delivery", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  61. Li, Z., Xu, J., Sun, G., Banerjee, D., Zheng, J., Woodard, P., Moore, D.A. and Wooley, K.L. "Labeling of Shell Crosslinked Nanoparticles (SCKs) for MRI", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  62. Berezin, M., Akers, W., Almutairi, A., Fréchet, J. M.J., Achilefu, S. "Monitoring Biodegradation of Near-Infrared Fluorescent Stealth Nanoparticles by Time-Domain Fluorescence Imaging", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  63. Fan, J and Achilefu, S. "Synthesis and Application of Gold-Nanoparticle-Peptide Conjugates to Detect Protease by Fluorescence Resonance Energy Transfer", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  64. Wooley, K.L. "Fundamental Aspects of the Preparation and Study of Discrete Nanoscale Objects, Designed for Biomedical Applications", Phi Lambda Upsilon Lectureship, Kansas State University, Department of Chemistry, Manhattan, Kansas, April 5, 2007.
  65. Wooley, K.L. "Robust nanostructured materials for fundamental studies and applications in nanomedicine", Etter Memorial Lectureship in Chemistry, University of Minnesota, Department of Chemistry, Minneapolis, MN, April 12, 2007.
  66. Wooley, K.L. "Crafting organic nanostructures with well-defined size, shape, structure and properties", Smith College, Department of Chemistry, Northampton, MA, April 26, 2007.
  67. Rossin, R., Zhou, Z., Muro, S., Kozlowski, J., Welch, M.J., Muzykantov, V.R., Schuster, D. "PET imaging of lung endothelium with 64Cu-labeled ICAM-1 targeted nanoparticles", 17th International Symposium on Radiopharmaceutical Sciences in Aachen, Germany, April 30 - May 4, 2007.
  68. Hagooly, A., Pressly, E., Rossin, R., Fukukawa, K., Messmore, B., Hawker, C.J., Welch, M.J. "Novel nanocarriers for imaging and drug delivery: in vivo evaluation of 64Cu-labeled PEG Graft Copolymers", 17th International Symposium on Radiopharmaceutical Sciences in Aachen, Germany, April 30 - May 4, 2007.
  69. Wooley, K.L. "Advancing Synthetic Organic Chemistry Concepts Toward Nanoparticles and Nanocages: Convergent and divergent approaches, originating from well-defined block copolymers and brush block copolymers, respectively", Dow Lecturer in Organic Chemistry, Massachusetts Institute of Technology, Department of Chemistry, Cambridge, MA, May 4, 2007.
  70. Rossin, R., Abendschein, D., Zheng, J., Sharp, T., Woodard, G.E., McQuade, M.J., Welch, M.J., Woodard, P.K. "64Cu-Labeled natriuretic peptide: a promising tracer for atherosclerotic plaque molecular imaging with PET", Oral presentation at the 54th SNM Annual Meeting, June 2-6, 2007, Washington, D.C. (J Nucl Med, 2007, 48 (Suppl. 2), 103P).
  71. Wooley, K.L. "Application of Synthetic Organic Chemistry Concepts and Methodologies Toward the Construction of Nanoscopic Target Molecules", 40th National Organic Chemistry Symposium, Duke University, Durham, North Carolina, June 5, 2007.
  72. Wooley, K.L. "Current Research in Nanotechnology and Its Applications to Medicine", Cornerstone Life Science Connections Program, Washington University, St. Louis, MO, June 25, 2007.
  73. Akers W., Berezin M., Almutairi A., Fréchet J., Achilefu S. "Imaging Molecular Processes by Optical Methods", 34-th annual meeting of Society of Controlled Release Society, Long Beach, CA, July 7-11, 2007.
  74. Wooley, K.L. "The Transformation of Block Copolymers into Bulk Composite Materials that Present Complex Features and into Discrete Nanoscale Objects", Milliken Research Corporation, Spartanburg, SC, August 3, 2007.
  75. Wooley, K.L. "From Dendrimers to Supramolecular and Covalent Nanostructures", 234th American Chemical Society National Meeting, Boston, MA, August 19, 2007.
  76. Fiamengo, A.L., Li, Z., Sun, G. Xu, J., Wooley, K.L., Anderson, C.J. "Binding affinity determination of RGD-functionalized shell crosslinked nanoparticles to αvβ3 and αvβ5 integrins", 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  77. Oquare, B.Y., Fang, H., Taylor, J.-S. "Peptide nucleic acide (PNA) FRET agents for imaging gene expression", Abstracts of Papers, 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007, MEDI-104.
  78. Fang, H., Oquare, B.Y., Zhang, Y., Taylor, J.-S. "Antisense cassette for gene expression imaging", Abstracts of Papers, 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007, BIOL-168.
  79. Powell, K.T., Anderson, C.J., Wooley, K.L. "Probing the Effect of Visual and Kinesthetic Teaching Methodologies on Middle School Science Students", 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  80. Li, Y.; Du, W.; Sun, G.; Wooley, K.L. "Preparation of Shell Crosslinked Nanoparticles Containing pH Sensitive Crosslinkers for Drug Delivery", PMSE, 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  81. Almutairi, A., Rossin, R., Shokeen, M., Berezin, M., Akers, W., Guillaudeu, S., Anderson, C., Achilefu, S., Welch, M.J., Fréchet, J.M.J 'Nanomaterials for biomedical imaging', American Chemical Society-Academic Employment Initiative Fall National Meeting, Boston, MA, USA, August 2007.
  82. Almutairi, A., Rossin, R., Shokeen, M., Berezin, M., Akers, W., Guillaudeu, S., Anderson, C., Achilefu, S., Welch, M.J., Fréchet, J.M.J, "Designing nanoscale carriers for bioactive agents", American Chemical Society-Academic Employment Initiative Fall National Meeting, Boston, MA, USA, August 2007.
  83. Li, Y.; Du, W.; Sun, G. and Wooley, K. L. "Preparation of Shell Crosslinked Nanoparticles Containing pH Sensitive Crosslinkers for Drug Delivery", 234th Meeting of the American Chemical Society, Boston, MA, August, 2007.
  84. Shokeen, M.1, Fiamengo, A.L.1, Rossin, R.1, Pressly, E.D.2, Fukukawa, A.2, Almutairi, A.3, Welch, M.J.1, Hawker, C.J.2, Fréchet, J.M.J.3, Anderson, C.J.1, 1Department of Radiology, Washington University School of Medicine, Saint Louis, USA; 2Materials Research Lab, University of California, Santa Barbara, CA, USA; 3Department of Chemistry, University of California, Berkeley, CA, USA. "Developing Optimized High Throughput Assays for Screening αvβ3 Targeting Nanoparticles for Diagnosis and Therapy", Oral presentation at the Joint Molecular Imaging Conference, Providence, Rhode Island, September 9, 2007.
  85. Wooley, K.L. "The Transformation of Block Copolymers into Bulk Composite Materials that Present Complex Features and into Discrete Nanoscale Objects", 3M ESPE Dental Products, St. Paul, MN, September 18, 2007.
  86. Wooley, K.L. "Synthetic Methodologies for the Preparation of Polymers and Nanoscale Objects", 29th Annual Bayer Lecture Series, University of Pittsburgh, Pittsburgh, PA, November 16, 2007.
  87. Wooley, K.L. "Synthetic Methodologies for the Preparation of Polymers and Nanoscale Objects I", Frontiers in Chemical Research Distinguished Lecture Series, Texas A&M University, College Station, TX, November 26, 2007.
  88. Wooley, K.L. "Synthetic Methodologies for the Preparation of Polymers and Nanoscale Objects II", Frontiers in Chemical Research Distinguished Lecture Series, Texas A&M University, College Station, TX, November 27, 2007.
  89. Wooley, K. L., "Integration of Syntheses, Physicochemical Characterization, and Biological Testing in vitro and in vivo to Address Significant Medical Needs", Frontiers in Chemical Research Distinguished Lecture Series, Texas A&M University, College Station, TX, November 28, 2007.
  90. Wooley, K. L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology", Society of Professors Emeriti, Washington University, St. Louis, MO, January 14, 2008.
  91. Berezin, M.K., Lee, H., Akers, W., Nikiforovich, G., and Achilefu, S., "Fluorescent lifetime of near infrared dyes for structural analysis of serum albumin", SPIE—The International Society for Optical Engineering, San Jose, CA, January 22, 2008.
  92. Berezin, M.K., Almutairi, A., Guillaudeu, S.J., Nikiforovich, G., Akers, W., Achilefu, S., and Fréchet, J.M.J., "Activatable biodegradable nanoprobes for NIR fluorescence intensity & lifetime imaging", Siteman Center of Cancer Nanotechnology Excellence-Program of Excellence in Nanotechnology (SCCNE-PEN) Seminar, St. Louis, MO, February 2, 2008.
  93. Wooley, K.L. "Synthetic Methods for the Preparation of Well-defined Nanostructures, Designed as Versatile Scaffolds for Imaging and Therapy of Acute Vascular Injury, Cancer, and other Targets", Institute for Environmental Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, February 8, 2008.

  94. Shokeen M., "Targeted Nanoparticles for Diagnosis and Therapy", 4th Annual Postdoc Scientific Symposium, Washington University School of Medicine, February 26, 2008. Invited Talk

  95. Wooley, K. L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology", University of California-Irvine, Department of Nanotechnology, Irvine, CA, March 12, 2008.
  96. Lee, N.S., Neumann, W.L., Freskos, J.N., Marzan, T.A., Shieh, J.J., Dorshow, R.B., Wooley, K.L., "Photonic shell-crosslinked nanoparticle probes for optical imaging and monitoring", Biomedical Optics Topical Meeting in Optical Society of America, St. Petersburg, FL, March 16, 2008.
  97. Powell, K.T., Du, W., Anderson, C.J., Wooley, K.L.  "Scientific Leadership:  The true purpose of the academy", March 15, 2008, Southern Illinois University Edwardsville, East Saint Louis Education Center, Saint Louis, MO.
  98. Nyström, A. M., Wooley, K.L. "Tuning the crystalline melting point of shell crosslinked nanoparticles", American Chemical Society, Division of Polymer Chemistry, New Orleans, LA, April 2008, Polymer Preprints 2008, 49(1), 1097-1098.
  99. Nyström, A. M., Xu, J., Wooley, K.L. "Uptake and release of therapeutic agents from shell-crosslinked nanoparticles", Meeting of the American Chemical Society, New Orleans, LA, PMSE Preprints, April 2008.
  100. Wooley, K. L., "Shell Crosslinked Knedel-like (SCK) Nanoparticles and Hyperbranched Fluoropolymers (HBFP)", Johns Hopkins University, Department of Chemistry, Baltimore, MD, April 1, 2008.
  101. Lee, N.S., Neumann, W.L., Freskos, J.N., Marzan, T.A., Shieh, J.J., Dorshow, R.B., Wooley, K.L., "Photonic shell-crosslinked nanoparticle probes for optical imaging and monitoring", 235th American Chemical Society National Meeting, New Orleans, LA, April 10, 2008.
  102. Wooley, K. L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology", Central Michigan University, Mt. Pleasant, MI, April 23, 2008.
  103. McCommis, K.S., Rossin, R., Abendschein, D.R., Ochoa, B., Woodard, G.E., Welch, M.J., Woodard, P.K., Zheng, J.  "Detection of atherosclerotic plaque progression: Correlation of contrast MRI with PET using 64Cu-labeled Natriuretic peptide", Oral presentation: International Society of Magnetic Resonance in Medicine Annual Meeting; May 2008, Toronto.
  104. Wooley, K. L. "What is Nano and Why is it Important?", Nanofuture:  You and the Environment Series, Saint Louis Science Center and the Academy of Science of St. Louis, St. Louis, MO, May 6, 2008.
  105. Achilefu, S.  "Nanomolecules and Nanoparticles in Optical Imaging of Tumors", Nanotechnology Seminar Series by the Center for Nano Technology, May 5-7, 2008, Center for Nanotechnology, University of Washington, Seattle, WA.
  106. McCommis, K.S., Rossin, R., Abendschein, D.R., Ochoa, B., Woodard, G.E., Welch, M.J., Woodard, P.K., Zheng, J.  "Detection of Atherosclerotic Plaque Progression:  Correlation of Contrast MRI with PET using 64Cu-labeled Natriuretic Peptide".  Proceedings of the International Society for Magnetic Resonance in Medicine, p.99, #519, May 7, 2008, Toronto.
  107. Anderson, C.J., Welch, M.J.  "Graduate training in imaging sciences at Washington University", invited presentation at the American Nuclear Society Annual Meeting, Anaheim, CA, June 11, 2008. 
  108. Liu, Y., Hagooly, A., Sun, G., Rossin, R., Xu, J., Nyström, A. M., Li, Z., Wooley, K. L. and Welch, M. J., "In vivo evaluation of 64Cu labeled PEGylated shell crosslinked nanoparticles (SCKs) as candidates for imaging and drug delivery", Oral presentation at the 55th SNM Annual Meeting, June 14-18, 2008, New Orleans, LA., (J. Nucl Med, 2008, 49(Suppl.1), 44P, 174).
  109. Achilefu, S., Akers, W., "Applications of Optical Imaging", National Cancer Institute 2008 Cancer Research Imaging Camp, June 15-20, 2008, Duke University, Durham, NC.
  110. Wooley, K. L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology:  With an emphasis on devices for nanomedicine", Rhodia, Inc., Bristol, PA, June 23, 2008.
  111. Nyström, A. M., Wooley, K.L.  "Tuning the Release of Active Components from Nanoparticles by Defining the Crystallinity of the Particle Core", 2008 Intn'l. Conf on Nanotechnology for the Forest Products, St. Louis, MO, June 25, 2008.
  112. Achilefu, S., "Hidden treasures of invisible light-Harnessing the power of light for imaging and treating diseases", Biomed RAP Lecture, July 15th, 2008, Washington University School of Medicine, St. Louis, MO.
  113. Achilefu, S., et al, "Fluorescence lifetime imaging in vivo", Gordon Research Conference, Lasers in Medicine & Biology, July 20-25, 2008, Holderness School, Holderness, NJ.
  114. Achilefu, S., et al, "Fluorescence lifetime imaging of tumors using near infrared fluorescent molecular probes", 236th ACS National Meeting & Exposition, August 17-21, 2008, Philadelphia, PA.
  115. Achilefu, S., et al, "Chemical and biochemical contrast strategies for optical imaging of molecular processes in vivo", 236th ACS National Meeting & Exposition, August 17-21, 2008, Philadelphia, PA.

  116. Anderson, C.J., Welch, M.J.  "Graduate training in imaging sciences at Washington University", invited presentation, American Chemical Society Fall Meeting, Philadelphia, PA, August 19, 2008. 

  117. Fiamengo, A. L., Ye, Y., Achilefu, S., Anderson, C.J.  "Binding affinity and cellular internalization of αvβ3 targeting ligands for molecular imaging of cancer and cardiovascular disease", Oral presentation, American Chemical Society Fall Meeting, Philadelphia, PA, August 19, 2008. 
  118. McCommis, K.S., Liu, Y., Abendschein, D.R., Woodard, G.E., Welch, M.J., Woodard, P.K., Zheng, J.  "Expression of NPR-C in Neointimal Plaque Progresses Parallel with Extracellular Matrix:  Direct Assessment In Vivo with PET and MRI".  Submitted to American Heart Association Meeting;  November 2008, New Orleans, LA.

Patents:

  1. Wooley, K. L., "Cell-permeable Nanoconjugates of Shell-crosslinked Knedel (SCK) and Peptide Nucleic Acids ("PNAs") with mRNA-targeting Sequences for Early Diagnosis and Therapy of Cancer", PCT Int. Appl. 2006, WO 2006044716.

  2. Neumann, W. L., Rajagopalan, R. Dorshow, R. B., Shieh, J. J., Freskos, J., N., Lee, N. S., Wooley, K. L., “Photonic shell-core crosslinked and functionalized nanostructures for biological imaging, anatomical visualization, physiological monitoring and phototherapy,” US Provisional Patent #60/986,171, filed Nov. 7, 2007.

  3. Woodard, P., Rossin, R., Woodard, G., Welch, M., "Natriuretic peptide-mediated imaging of artherosclerotic plaque", US Provisional Patent #61/130681, filed June 2, 2008.
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