Principal
Investigator
Michael J. Welch
Wash Univ - Med

Co-Principal Investigator
Karen L. Wooley
Texas A&M

Program Official
Denis B. Buxton
NHLBI

-- PROJECTS --
Project 1
Karen L. Wooley

Project 2
Carolyn L. Cannon

Project 3
Steven L. Brody

Project 4
Pamela K. Woodard

Dev Proj 1
Michael J. Welch

Dev Proj 2
Mikhail Y. Berezin

Core-PROD
Craig J. Hawker

Core-SKILLS
Joseph P. Culver

Seminar, July 14
Omid Farokhzad,MD
Farrell Holden Audit.
2:00- 3:00 p.m.
Omid C. Farokhzad, M.D.


Press Release
New PEN announced

Monthly Meetings
 CSRB Conf Room #4402 at WUSM

PEN Admin Center (ACPEN website)
Click here to learn about the 4 PENs
Inter-PEN website

Publications, Presentations & Patents

Publications, presentations and patents resulting from PEN-funded research.


Or, visit PubMed to see Current PEN and Initial PEN publications.

Current PEN | Initial PEN


Manuscripts

  1. Huafeng Fang; Xuan Yue; Xiaoxu Li; John-Stephen Taylor. 'Identification and characterization of high affinity antisense PNAs for the human unr (upstream of N-ras) mRNA which is uniquely overexpressed in MCF-7 breast cancer cells', Nucleic Acids Res. 2005, 33, 6700-6711.  PMCID: PMC1297704.
  2. Lee, Cameron C.; MacKay, John A.; Fréchet, Jean M. J.; Szoka, Francis C. 'Designing dendrimers for biological applications', Nature Biotechnology 2005, 23(12), 1517-1526.
  3. Kwon, Young Jik; James, Edward; Shastri, Nilabh; Fréchet, Jean M. J.  'In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles'. Proc. Nat. Acad. Sci., 2005, 102(51), 18264-18268.
  4. Wu, P.; Malkoch, M.; Hunt, J.N.; Vestberg, R.; Kaltgrad, E.; Finn, M.G.; Fokin V.V.; Sharpless, K.B.; Hawker, C.J. 'Multivalent, bifunctional dendrimers prepared by click chemistry.' Chem. Comm. 2005, 5775-5777.
  5. Goodwin, Andrew P.; Mynar, Justin L.; Ma, Yingzhong; Fleming, Graham R.; Fréchet, Jean M. J. 'Strategy for two-photon light sensitive polymeric micelle design'. Polym. Mat. Sci. Eng., 2006, 94, 131-132.
  6. Mynar, Justin L.; Lowery, Thomas J.; Wemmer, David E.; Pines, Alexander; Fréchet, Jean M. J.. 'Xenon Biosensor Amplification via Dendrimer-Cage Supramolecular Constructs.' Journal of the American Chemical Society 2006, 128(19), 6334-6335.
  7. O Reilly, R.; Joralemon, M. J.; Hawker, C. J.; Wooley, K. L. 'Fluorogenic 1,3-Dipolar Cycloaddition within the Hydro phobic Core of a Shell Cross-Linked Nanoparticle' J. Polym. Sci., Part A: Polym. Chem. 2006, 44(17), 5203-5217.
  8. R. Rossin, E. Pressly, K. Fukukawa, B. Messmore, J.L. Turner, M.J. Joralemon, M.L. Becker, C. Hawker, K.L. Wooley, M.J. Welch. 'Evaluation of 64Cu-radiolabeled nanoparticles for the diagnosis and treatment of disease' in Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine 7 U. Mazzi (ed.), Proc. of the 7th International Symposium on Technetium in Chemistry and Nuclear Medicine, 2006.
  9. Standley, S. M.; Mende, I.; Goh, S. L.; Kwon, Y. J.; Beaudette, T. T.; Engelman, E. G.; Fréchet, J. M. J. 'Incorporation of CpG Oligonucleotide Ligand into Protein-Loaded Particle Vaccines Promotes Antigen-Specific CD8 T-Cell Immunity' in Bioconj. Chem., 2007, 18(1), 77-83.
  10. Jain, R.; Standley, S. M.; Fréchet, J. M. J. 'Synthesis and Degradation of pH-Sensitive Linear poly(amidoamine)s' in Macromolecules, 2007, 40(3), 452-457.
  11. Lee, C. C.; Gillies, E. R.; Fox, M. E.; Guillaudeu, S. J.; Fréchet, J. M. J.; Dy, E. E.; Szoka, F. C. 'A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas' in Proc. Nat. Acad. Sci.. 2006, 103, 16649-54.
  12. Lee, C. C.; Cramer, A. T.; Szoka, F. C.; Fréchet, J. M. J. 'An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin' in Bioconjugate Chemistry., 2006, 17, 1364-13685.
  13. Lee, C. C.; Fréchet, J. M. J. 'Synthesis and conformation of dendronized poly(L-lysine)' in Macromolecules, 2006, 39, 476-48.
  14. Venkataraman, S.; Wooley, K. L. 'ATRP from an Amino Acid-Based Initiator: A Facile Approach for Functionalized Polymers' in Macromolecules. 2006, 39(26), 9661-9664.
  15. O’Reilly, R. K.; Joralemon, M. J.; Hawker, C. J.; Wooley, K. L. 'Facile Syntheses of Surface-functionalized Micelles and Shell Cross-linked Nanoparticles' in J. Polym. Sci., Part A: Polym. Chem. 2006, 44, 5203-5217.
  16. Sun, G.; Cheng, C.; Wooley, K. L. 'Reversible Addition Fragmentation Chain Transfer (RAFT) Polymerization of 4-Vinylbenzaldehyde' in Macromolecules, 2007, 40(4) 793-795.  PMCID: PMC2597404.
  17. Van Horn, B. A.; Wooley, K. L. 'Toward Crosslinked Degradable Polyester Materials: Investigations into the compatibility and use of reductive amination chemistry for crosslinking' in Macromolecules, 2007, 40(5) 1480-1488.
  18. O’Reilly, R. K.; Joralemon, M. J., Hawker, C. J.; Wooley, K. L. 'Preparation of Orthogonally-functionalized Core Click Cross-linked Nanoparticles', New J. Chem., 2007, 31(5) 718-724.
  19. Powell, K. T.; Cheng, C.; Wooley, K. L. 'Complex Amphiphilic Hyperbranched Fluoropolymers by Atom Transfer Radical Self-condensing Vinyl Copolymerization', Macromolecules, 2007, 40(13) 4509-4515.  PMCID: PMC2531251.
  20. Xu, J.; Sun, G.; Rossin, R.; Hagooly, A.; Li, Z.; Fukukawa, K.; Messmore, B. W.; Moore, D. A.; Welch, M. J.; Hawker, C. J.; Wooley, K. L. 'Labeling of Polymer Nanostructures for Medical Imaging: Importance of charge density, spacer length, and crosslinking extents', Macromolecules, 2007, 40(9) 2971-2973.  PMCID: PMC2531250.
  21. Mynar, J.L.; Goodwin, A.P.; Cohen, J.A.; Ma, Y.; Fleming, G.R.; Fréchet, J.M.J. 'Two-photon degradable supramolecular assemblies of linear-dendritic copolymers.', Chemical Communications, 2007, (20), 2081-2082.
  22. Berezin, M. Y.; Lee, H.; Akers, W.; Nikiforovich, G.; Achilefu, S. 'Ratiometric Analysis of Fluorescence Lifetime for Probing Binding Sites in Albumin with Near Infrared Fluorescent Molecular Probes.' Photochem. Photobiol., 2007, 83, 1-8.
  23. Berezin, M. Y.; Lee, H.; Akers, W.; Achilefu, S. 'Near infrared dyes as lifetime solvatochromic probes for micropolarity measurements of biological systems', Biophys J 2007, 93 (8), 2892-9.  PMCID:  PMC1989699.
  24. Bartels, J.W; Cheng, C.; Powell, K.T.; Xu, J.; Wooley, K.L. 'Hyperbranched Fluoropolymers and their Hybridization into Complex Amphiphilic Crosslinked Copolymer Networks', Macromolecular Chemistry and Physics, 2007, 208(15), 1676-1687.
  25. Sun, G.; Xu, J.; Hagooly, A.; Rossin, R.; Li, Z.; Moore, D.A.; Welch, M.J.; Wooley, K.L. 'Strategies for Optimized Radiolabeling of Nanoparticles for in vivo MicroPET Imaging;', Advanced Materials (Weinheim, Germany), 2007, 19(20), 3157-3162.
  26. Goodwin, A.P., Lam, S.S., Fréchet, J.M.J. 'Rapid, Efficient Synthesis of Heterobifunctional Biodegradable Dendrimers', Journal of American Chemical Society, 2007, 129(22), 6994-6995.
  27. Pressly, E. D.; Rossin, R.; Hagooly, A.; Fukukawa, K.; Messmore, B. W.; Wooley, K. L.; Welch, M. J.; Lamm, M.; Hule, R.; Pochan, D. J.; Hawker, C. J., 'Rapid Structural Effects on the Biodistribution and Positron Emission Tomography (PET) Imaging of Well-defined 64Cu-Labeled Nanoparticles Comprised of Amphiphilic Block Graft Copolymers', Biomacromolecules, 2007, 8, 3126-3134.
  28. Li, Y.; Sun, G.; Xu, J.; Wooley, K. L. ; 'Shell Crosslinked Nanoparticles: A progress report of their design for drug delivery', a chapter in the book 'Nanotechnology in Therapeutics: Current technology and applications' J. Zach Hilt, J. Brock Thomas and Nicholas A. Peppas editors, Horizon Bioscience, Wymondham, UK, 2007, 381-407, ISBN-13: 978-1-904933-29-8.
  29. Chen, Z.; Cheng, C.; Germack, D. S.; Gopalan, P.; Van Horn, B. A.; Venkataraman, S.; Wooley, K. L.; 'Complex Functional Macromolecules' Chapter 18 of Volume 2: 'Elements of Macromolecular Structural Control' within the book series 'Macromolecular Engineering', edited by K. Matyjaszewski, Y. Gnanou, and L. Leibler, Wiley-VCH, Weinheim, 2007, 2, 1341-1385, ISBN-13: 978-3-527-31446-1.
  30. Cheng, C.; Powell, K.T.; Khoshdel, E.; Wooley, K. L.; 'Polydimethylsiloxane- (PDMS-) Grafted Fluorocopolymers by a "Grafting through" Strategy Based on Atom Transfer Radical (Co)polymerization', Macromolecules; (Article); 2007, 40(20), 7195-7207.
  31. Cheng, C.; Sun, G.; Khoshdel, E.; Wooley, K.L. 'Well-Defined Vinyl Ketone-Based Polymers by Reversible Addition-Fragmentation Chain Transfer Polymerization', J. Am. Chem. Soc., 2007, 129(33) 10086-10087.
  32. Schuster, D.P. 'The opportunities and challenges of developing imaging biomarkers to study lung function and disease', American journal of respiratory and critical care medicine, 2007, 176(3), 224-30.
  33. Connal, L. A.; Vestberg, R.; Hawker, C.J.; Qiao, G.G. 'Synthesis of Dendron Functionalized Core Cross-linked Star Polymers', Macromolecules, 2007, 40(22), 7855-7863.
  34. An, Z.; Shi, Q.; Tang, W.; Tsung, C.K.; Hawker, C.J.; Stucky, G.D. 'Facile RAFT Precipitation Polymerization for the Microwave Assisted Synthesis of Well-Defined, Double Hydrophilic Block Copolymers and Nanostructured Hydrogels', J. Am. Chem. Soc, 2007, 129(46), 14493-14499.
  35. Li, Y.; Akiba, I.; Harrisson, S.; Wooley, K.L. 'Facile Formation of Uniform Shell Crosslinked Nanoparticles with Built-in Functionalities from N-hydroxysuccinimide-activated Amphiphilic Block Copolymers', Adv. Func. Mater., 2007, 18, 551-559.
  36. Zheng J., Ochoa E., Misselwitz B., Yang D., El Naqa I., Woodard P.K., Abendschein D. 'Targeted contrast agent helps to monitor advanced plaque during progression: A magnetic resonance imaging study in rabbits', Invest Radiol., January 2008, 43(1):49-55.
  37. Rossin, R.; Muro, S.; Welch, M. J.; Muzykantov, V.R.; Schuster, D.P., 'In vivo imaging of 64Cu-labeled polymer nanoparticles targeted to the lung endothelium', J Nucl Med, January 2008, 49(1), 103-11.
  38. Almutairi, A., Berezin, M.Y., Guillaudeu, S., Achilefu, S., Fréchet, J.M.J. “Biodegradable pH sensing dendritic nanoprobes for near infrared fluorescence lifetime and intensity imaging.” Journal of the American Chemical Society, January 2008, 130(2), 444-445.
  39. Van Horn, B. A.; Iha, R. K.; Wooley, K. L. “Sequential and single-step, one-pot strategies for the transformation of hydrolytically-degradable polyesters into multi-functional systems”, Macromolecules, February 2008, 41(5), 1618-1626.
  40. Fukukawa, K.; Rossin, R.; Hagooly, A.; Pressly, E. D.; Hunt, J. N.; Messmore, B. W.; Wooley, K. L.; Welch, M. J.; Hawker, C. J., 'Synthesis and characterization of core-shell star copolymers for in vivo PET imaging applications', Biomacromolecules, March 2008, 9(4),  1329-1339.
  41. Nyström, A. M.; Wooley, K. L. 'Construction of thermoresponsive SCKs through tuning the crystalline melting point of the core domain', Soft Matter, March 2008, 4(4), 849-858.
  42. Cohen, J.L., Almutairi, A., Cohen, J.A., Bernstein, M., Brody, S.L., Schuster, D., Fréchet, J.M.J.  “Enhanced cell penetration of acid degradable particles functionalized with cell penetrating peptides.” Bioconjugate Chemistry, April 2008, 19(4), 876-881.
  43. Ma, J.; Cheng, C.; Sun, G.; Wooley, K. L. 'A polarity-activation strategy for the high incorporation of 1-alkenes into functional copolymers via RAFT copolymerization', J. Am. Chem. Soc., April 2008, 46, 3488-3498.
  44. Takizawa, K.; Nulwala, H.; Thibault, R. J.; Lowenhielm, P.; Wooley, K. L.; Hawker, C. J. “Facile Routes for the Syntheses of 4-Vinyl-1,2,3-Triazole Monomers by Click Azide/Acetylene Coupling”, J. Polym. Sci., Part A: Polym. Chem., May 2008, 46(9), 2897-2912.
  45. Sun, G.; Hagooly, A.; Xu, J.; Nyström, A. M.; Li, Z.; Rossin, R.; Moore, D. A.; Wooley, K. L.; Welch, M. J. 'Facile, Efficient Approach to Accomplish Tunable Chemistries and Variable Biodistributions for Shell Cross-Linked Nanoparticles', Biomacromolecules, May 2008, 9(7), 1997-2006.
  46. MacFarland, D.K.; Walker, K. L.; Lenk, R. P.; Wilson, S. R.; Kumar, K.; Kepley, C. L.; Garbow, J.R., "Hydrochalarones: A Novel Endohedral Metallofullerene Platform for Enhancing Magnetic Resonance Imaging Contrast", J. Med. Chem., July 2008.  PMCID:  PMC2630425.
  47. Nyström, A. M., Xu, Z., Xu, J., Taylor, S., Nittis, T., Stewart, S. A., Leonard, J., Wooley, K. L.  "SCKs as nanoparticle carriers of doxorubicin:  investigation of core composition on the loading, release and cytotoxicity profiles", Chem. Commun., August 2008, 3579-3581.  PMCID: PMC2828943.
  48. Zhou, C.; Qi, K.; Wooley, K. L.; Walker, A. V. 'Time-of-flight secondary ion mass spectrometry, fluorescence microscopy and scanning electron microscopy: Combined tools for monitoring the process of patterning and layer-by-layer assembly of synthetic and biological materials', Colloids and Surfaces B, Biointerfaces, August 2008,  65(1), 85-91.
  49. Nyström, A. M., Wooley, K. L.  "Thiol-functionalized shell crosslinked knedel-like (SCK) nanoparticles:  a versatile entry for their conjugation with biomacromolecules", Tetrahedron, September 2008, 64, 8543-8552.  PMCID:  PMC2597865
  50. Lee, N.S.; Li, Y.; Ruda, C.M.; Wooley, K.L. “Aqueous-only, pH-induced nanoassembly of dual pKa-driven contraphilic block copolymers,” Chem. Commun., September 2008, 42, 5339-5341.  PMCID:  PMC2703793
  51. Zhang, K.; Fang, H.; Chen, Z.; Taylor, J.-S. A.; Wooley, K. L.  "Shape Effects of Nanoparticles Conjugated with Cell-Penetrating Peptides (HIV Tat PTD) on CHO Cell Uptake", Bioconjugate Chem., September 2008, 19, 1880-1887.  PMCID:  PMC2697497
  52. Li, Y.; Du, W.; Sun, G.; Wooley, K. L.  "pH-Responsive Shell Crosslinked Nanoparticles with Hydrolytically-labile Crosslinks", Macromolecules, September 2008, 41, 6605-6607.  NIHMSID:  112990
  53. Shokeen M; Fettig N M; Rossin R., "Synthesis, in vitro and in vivo evaluation of radiolabeled nanoparticles",  The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology  (September 2008),  52(3),  267-77.
  54. Akers, W., Berezin, M., Lee, H., Achilefu S.   "Predicting In Vivo Fluorescence Lifetime Behavior of NIR Fluorescent Contrast Agents Using In Vitro Measurements", Journal of Biomedical Optics, Sept-Oct 2008, 13(5), 054042/1 - 054042/9.  PMCID:  PMC2744956. 
  55. Bachelder, E.M.; Beaudette, T.T., Broaders, K.E., Paramonov, S.E.; Dashe, J.; Fréchet, J.M.  "Acid-degradable polyurethane particles for protein-based vaccines: biological evaluation and in vitro analysis of particle degredation products", Mol. Pharm., Sept-Oct 2008, 5(5), 876-84.
  56. Almutairi, Adah; Akers, Walter J.; Berezin, Mikhail Y.; Achilefu, Samuel; Fréchet, Jean M. J., "Monitoring the Biodegradation of Dendritic Near-Infrared Nanoprobes by in Vivo Fluorescence Imaging",  Molecular Pharmaceutics, October 2008, 5, 1103-1110.  PMCID: 2772156
  57. Du, W., Nyström, A. M., Lei, Z., Powell, K. T., Li, Y. Cheng, C., Wickline, S. A., Wooley, K. L.  "Amphiphilic Hyperbranched Fluoropolymers as Nanoscopic 19F-Magnetic Resonance Imaging Agent Assemblies", Biomacromolecules, October 2008, 9(10), 2826-2833, PMCID:  PMC2744969
  58. Oquare, B.Y.; Taylor, J.-S.  "Synthesis of Peptide Nucleic Acid FRET Probes via an Orthogonally Protected Building Block for Post-Synthetic Labeling of Peptide Nucleic Acids at the 5-Position of Uracil",  Bioconjug. Chem., November 2008.  PMCID: PMC2763603.
  59. Du, W.; Xu, Z., Nyström, A.M.; Zhang, K.; Li, Y.; Leonard, J.; Wooley, K.L.; “19F- and Fluorescently-labeled Micelles as Nanoscopic Assemblies for Chemotherapeutic Delivery”, Bioconjugate Chemistry, 19(12), 2492-2498, December 2008.  PMCID: PMC2703787.
  60. Cohen, J.; Beaudette, T.T.; Tseng, W.W.; Bachelder, E.M.; Mende, I; Engleman, E.G.; Fréchet, J. M. J.; "T-cell Activation by Antigen-loaded pH-sensitive Hydrogel Particles In Vivo: The Effect of Particle Size", Bioconjugate Chemistry, December 2008, 20(1), 111-119.  PMCID:  PMC2640420
  61. Ma, J.; Cheng, C.; Sun, G.; Wooley, K.L.  "Well-defined polymers bearing pendant alkene functionalities via selective RAFT polymerization", Macromolecules, December 2008, 41(23), 9080-9089.  NIHMSID:  121095
  62. Zhang, K; Rossin, R.; Hagooly, A.; Chen, Z.; Welch, M.J.; Wooley, K.L.  "Folate-mediated cell uptake of shell-crosslinked spheres and cylinders", J. Polymer Sci., Part A:  Polym. Chem., 2008, 46(22), 7578-7583.  PMCID: PMC2765714.
  63. Almutairi, A.; Rossin, R.; Shokeen, M.; Hagooly, A.; Ananth, A.; Capoccia, B.; Guillaudeu, S.; Abendschein, D.; Anderson, C.J.; Welch, M.J.; Fréchet, J. M. J.; "Biodegradable dendritic positron-emitting nanoprobes for the noninvasive imaging of angiogenesis". Proc. Nat. Acad. Sci.; January 20, 2009; 106(3), 685-690.  PMCID:  PMC2630081.
  64. Nyström, A.M.; Bartels, J.W.; Du, W., Wooley, K. L.; “Perfluorocarbon-loaded Shell Crosslinked Knedel-like Nanoparticles:  Lessons regarding polymer mobility and self assembly”, Journal of Polymer Science Part A: Polymer Chemistry, February 2009, 47, 1023-1037.  PMCID: PMC2779516.
  65. Zhang, K.; Fang, H.; Wang, Z.; Taylor, J.-S.; Wooley, K. L.  "Cationic shell-crosslinked knedel-like nanoparticles for highly effecient gene and oligonucleotide transfection of mammalian cells",  Biomaterials, February 2009, 30, 968-977.  NIHMSID:  98523
  66. Sun, G; Fang, H.; Cheng, C.; Lu, P.; Zhang, K.; Walker, A. V.; Taylor, J.-S. A.; Wooley, K. L.  "Benzaldehyde-functionalized Polymer Vesicles", ACS Nano, March 2009, 3(3), 673-681.  PMCID: PMC2661032.
  67. Goiffon, R.J.; Akers, W.J.; Berezin, M.Y.; Lee, H.; Achilefu, S.  "Dynamic noninvasive monitoring of renal function in vivo by fluorescence lifetime imaging",J Biomed Opt, March-April 2009, 14(2) 020501.
  68. Lee, N.S.; Sun, G.; Neumann, W.L.; Freskos, J.N.; Shieh, J.J.; Dorshow, R.B.; Wooley, K.L. “Photonic Shell-Crosslinked Nanoparticle Probes for Optical Imaging and Monitoring,” Adv. Mater., April 2009, 21(13), 1344-1348.  NIHMSID:  135431
  69. Fang, H.; Zhang, K.; Shen, G.; Wooley, K.L.; Taylor, J.-S.  "Cationic Shell-crosslinked Knedel-like (cSCK) Nanoparticles for Highly Efficient PNA Delivery", Molecular Pharmaceutics, April 2009, 6(2), 615-626.  PMCID: PMC2699773
  70. Shokeen, M.; Anderson, C. J.  "Molecular Imaging of Cancer with Copper-64 Radiopharmaceuticals and Positron Emission Tomography (PET)", Accounts of Chemical Research, 42(2), 832-841, July 2009.
  71. Hawker, C.  "Facile Preparation of Nanoparticles by Intramolecular Crosslinking of Isocyanate Functionalized Copolymers", Macromolecules, June 2009, 42(15), 5629-5635.  NIHMSID:  123501
  72. Liu, Y.; Ibricevic-Richardson, A.; Gunsten, S.; Cohen, J.L.; Kozlowski, J.; Fréchet, J.M.J.; Walter, M.J.; Welch, M.J.; Brody, S.L.; "Utility of a polyarginine peptide to mediate intracellular particle entry in vitro and following intra tracheal delivery", Amer. J. Resp. Crit. Care Med., 2009, A4972.
  73. Zhang, K.; Fang, H.; Shen, G.; Taylor, J.-S. A.; Wooley, K. L.;  "Well-defined Cationic Shell Crosslinked Nanoparticles (SCKs) for Efficienct Delivery of DNA or PNA", Proceedings of the American Thoracic Society, August 2009, 6(5), 450-457.  PMC2731805
  74. Shen, G.;  Fang, H.;  Song, Y.;  Bielska, A.;  Wang, Z.;  Taylor, J-S. A.;  "Phospholipid conjugate for intracellular delivery of peptide nucleic acids", Bioconjugate Chem., September 2009, 20(9), 1729-1736.  NIHMSID:  138800
  75. Li, Z.; Zhang, K.; Ma, J.; Cheng, C.; Wooley, K. L.  "Facile Synthesis of Cylindrical Molecular Brushes by a Sequential RAFT and ROMP "Grafting-through" Methodology", J. Polym. Sci., Part A:  Polym. Chem., September 2009, 47(20), 5557-5563.  NIHMSID  144222
  76. Paulusse, J. M. J.; Amir, R. J.; Evans, R. A.; Hawker, C.  "Free Radical Polymers with Tunable and Selective Bio- and Chemical Degradability", Journal of the American Chemical Society, 2009, 131(28), 9805-9812.  NIHMSID:  128194
  77. Beck, J. B.; Killops, K. L.; Kang, T.; Bayles, A.; Mackay, M. E.; Wooley, K. L.; Hawker, C. J.  "Facile Preparation of Nanoparticles by Intramolecular Crosslinking of Isocyanate-functionalized Copolymers", Macromolecules, 2009, 42(15), 5629-5635.  NIHMSID:  123501
  78. Anderson, C. J.; Ferdani, R.  "Copper-64 Radiopharmaceuticals for PET Imaging of Cancer:  Advances in Preclinical and Clinical Research", Cancer Biotherapy and Radiopharmaceuticals, 24(4), 379-393, August 2009.  PMCID:  PMC2794299.
  79. Liu, Y.; Ibricevic-Richardson, A.; Cohen, J. A.; Cohen, J.L.; Gunsten, S.P.; Fréchet, J. M. J.; Walter, M. J.; Welch, M. J.; Brody, S.L.  "Impact of hydrogel nanoparticle size and functionalization on in vivo behavior for lung imaging and therapeutics", Molecular Pharmaceutics, October 2009, 6(6), 1891-1902.  NIHMSID:  155731
  80. Zhang, K.; Fang, H.; Li, Z.; Ma, J.; Hohlbauch, S. V.; Taylor, J.-S. A.; Wooley, K. L.; "Composite Soft-Matter Nanoscale Objects:  Nanocylinder-templated assembly of nanospheres", Soft Matter, 2009, 5(19), 3585-3589.
  81. Sun, G.; Lee, N. S.; Neumann, W. L.;  Freskos, J. N.; Shieh, J. J.; Dorshow, R. B.; Wooley, K. L.;  "A Fundamental Investigation of Cross-linking Efficiencies within Discrete Nanostructures, Using the Cross-linker as a Reporting Molecule", Soft Matter, 2009, 5(18), 3422-3429.
  82. Welch, M. J.; Hawker, C. J.; Wooley, K. L.  "The Advantages of Nanoparticles for PET Imaging", J. Nucl. Med., 2009, 50, 1743-1746.
  83. Sun, G.; Berezin, M.Y.; Fan, J.; Lee, H.; Zhang, K.; Achilefu, S.I.; Wooley, K.L.  "Bright Fluorescent Nanoparticles for Developing of Potential Optical Imaging Contrast Agents", Nanoscale, 2010, 2, 548-558.
  84. Burke, D.; Iha, R. K.; Kade, M.; Nyström, A. M.; Wooley, K. L.; Hawker, C. J.  "Applications of Orthogonal, "Click" Chemistries in the Synthesis of Functional Soft Materials", Chem. Rev., 2009, 109(11), 5620-5686.
  85. Broaders, K. E.; Cohen, J. A.; Beaudette, T. T.; Bachelder, E. M.; Fréchet, J. M. J. "Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy", Proc. Nat. Acad. Sci., 2009, 106 (14), 5497-5502.  PMCID: PMC2666992.
  86. Amir, R .J.; Zhong, S.; Pochan, D. J.; Hawker, C. J. "Enzymatically Triggered Self-Assembly of Block Copolymers", Journal of the American Chemical Society (2009), 131 (39), 13949-13951.
  87. Beaudette, T. T.; Cohen, J. A.; Bachelder, E. M.; Broaders, K. E.; Cohen, J. L.; Engleman, E. G.; Fréchet, J. M. J. "Chemoselective ligation in the functionalization of polysaccharide-based particles",  J. Am. Chem. Soc., 2009, 131 (30), 10360-10361.
  88. Liu, Y.; Abendschein, D.; Woodard, G. E.; Rossin, R.; McCommis, K.; Zheng, J.; Welch, M. J.; Woodard, P. K.  "Molecular Imaging of Atherosclerotic Plaque with 64Cu-Labeled Natriuretic Peptide and PET", J Nucl Med, January 2010, 51(1), 85-91.  Epub 2009 Dec 15.
  89. Li, Y.; Hindi, K.; Watts, K.M.; Taylor, J. B.; Zhang, K.; Li, Z.; Hunstad, D. A.; Cannon, C. L., Youngs, W. J.; Wooley, K. L.  "Shell-Crosslinked Nanoparticles Carrying Silver Antimicrobials as Therapeutics", Chem. Commun., January 2010, 121-123.
  90. Zhang, K.; Fang, H.; Wang, Z.; Li, Z.; Taylor, J-S. A.; Wooley, K.L.  "Structure-activity relationships of cationic shell-crosslinked knedel-like nanoparticles:  shell composition and transfection efficiency/cytotoxicity", Biomaterials, March 2010, 31(7), 1805-13. PMCID: PMC2818368
  91. Glaus, C.; Rossin, R.; Welch, M.J.; Bao, G.  "In vivo evaluation of 64Cu-labeled magnetic nanoparticles as a dual-modality PET/MR imaging agent", Bioconjug. Chem., April 2010, 21 (4): 715-722.
  92. Cohen, J. A.; Beaudette, T. T.; Cohen, J. L., Broaders, K. E.; Bachelder, E. M.; Fréchet, J. M. J. "Acetal-modified dextran microparticles with controlled degradation kinetics and surface functionality for gene delivery in phagocytic and non-phagocytic cells", Advanced Materials, 2010.
  93. Lee, N.S.; Wooley, K.L. "Block Copolymer Synthesis Using a Nitroxide-mediated Radical Polymerization (NMP) Approach", Material Matters, 2010, 5(1), 1-4.
  94. Cauët, S.I.; Wooley, K.L.  "Kinetic investigation of the RAFT polymerization of p-acetoxystyrene", J. Polym. Sci., Part A:  Polym. Chem., 2010, 48(12), 2517-2524. PMCID: PMC2908413
  95. Du, W.; Li, Y.; Nyström, A.M.; Cheng, C.; Powell, K.T.; Wooley, K.L.  "Synthesis, Characterization, and Aqueous Self Assembly of Amphiphillic Poly(ethylene oxide)-functionalized Hyperbranched Fluoropolymers", J. Polym. Sci., Part A: Polym. Chem., 2010, 48(15), 3487-3496.
  96. Fang, H.; Shen, Y.; Taylor, J.-S.A.  "Native mRNA antisense-accessible sites library for the selection of antisense oligonucleotides, PNAs and siRNAs", RNA, 2010, July, 16(7), 1429-1435.
  97. Cohen, J.A.; Beaudette, T.T.; Cohen, J.L.; Broaders, K.E.; Bachelder, E.M.; Fréchet, J.M.J. "Acetal-modified dextran microparticles with controlled degradation kinetics and surface functionality for gene delivery in phagocytic and non-phagocytic cells", Advanced Materials, 2010, 22(32), 3593-7.
  98. Du, W.; Li, Y.; Nyström, A. M.; Cheng, C.; Powell, K. T.; Wooley, K. L. “Synthesis, Characterization, and Aqueous Self Assembly of Amphiphilic Poly(ethylene oxide)-functionalized Hyperbranched Fluoropolymers”, J. Polym. Sci., Part A:  Polym. Chem., 2010, 48(15), 3487-3496.
  99. Iha, R. K.; Van Horn, B. A.; Wooley, K. L. “Complex, Degradable Polyester Materials via Ketoxime Ether-based Functionalization:  Amphiphilic, multifunctional graft copolymers and their resulting solution-state aggregates”, J. Polym. Sci., Part A:  Polym. Chem., 2010, 48(16), 3553-3563.
  100. Bartels, J. W.; Cauët, S. I.; Billings, P. L.; Lin, L. Y.; Zhu, J.; Fidge, C.; Pochan, D. J.; Wooley, K. L. “Evaluation of Isoprene Chain Extension from PEO Macromolecular Chain Transfer Agents for the Preparation of Dual, Invertible Block Copolymer Nanoassemblies”, Macromolecules, 2010, 43(17), 7128-7139. NIHMSID: 27560
  101. Li, Z.; Zhang, K.; Ma, J.; Cheng, C.; Wooley, K. L. “Facile syntheses of cylindrical molecular brushes by a sequential RAFT and ROMP “grafting-through“ methodology”, J. Polym. Sci., Part A:  Polym. Chem., 2010, 47(20), 5557-5563. PMCID: PMC2776731
  102. Pochan, D. J.; Zhu, J.; Zhang, K.; Wooley, K. L.; Miesch, C.; Emrick, T. “Kinetic Control of Multicompartment and MultigeometryNanoparticle Assembly”, Soft Matter, 2011, DOI: 10.1039/C0SM00960A
  103. Pressly, E.D.; Amir, R.; Hawker, C.J. “Rapid Synthesis of Block and Cyclic Copolymers via Click Chemistry in the Presence of Copper Nanoparticles”, J. Polym. Sci. Part A, 2011, 49: 814–819.

Abstracts/Presentations

  1. Goodwin, A., Mynar, J.L., Ma, Y., Fleming, G.R., Fréchet, J.M.J. "Polymer Amphiphiles Sensitive to Two-Photon Near IR Irradiation", 231st American Chemical Society Meeting, Atlanta, GA., March 28, 2006.
  2. Fukukawa, K., Pressly, E., Gupta, N., Hawker, C. J. "Synthesis of PEGylated star microgel with core functionality for click chemistry by nitroxide-mediated radical polymerization", 231st American Chemical Society Meeting, Atlanta, GA, March 28, 2006, POLY-300.
  3. Li, Y., Harrisson, S., Wooley, K. L., "Biodegradable Nanoparticles for Drug Delivery", Graduate Student Research Symposium, St. Louis, MO, April, 1, 2006.
  4. R. Rossin, X. Sun, J.-S. Taylor, K.L. Wooley, M.J. Welch.  "Evaluation of 64Cu-Radiolabeled Targeted Nanoparticles for the Diagnosis and Treatment of Disease, Nanotechnologies and the Life Sciences", Burnham Institute 28th Annual Symposium, La Jolla, CA, 13-14 April 2006.
  5. Li, Y., Harrisson, S., Wooley, K. L., "Biodegradable Nanoparticles for Drug Delivery", 19th Missouri Organic Chemistry Day, Columbia, MO, April, 29, 2006.
  6. Fukukawa, K., Pressly, E., Gupta, N., Hawker, Craig J. "Synthesis of PEGylated star microgel with core functionality for click chemistry by nitroxide-mediated radical polymerization", CNST Nanotechnology Workshop, Urbana-Champaign, IL, May 4-5, 2006.
  7. Berezin, M., Akers, W., Bloch, S., Achilefu, S., "Roles of nanomolecules and nanomaterials in optical imaging of tumors in-vivo", CNST Nanotechnology Workshop, Urbana-Champaign, IL, May 4-5, 2006.
  8. M. Berezin, S. Bloch, Akers, W.,  Ye, Y., Liang, K., Achilefu,S., "Fluorescent nanosized and organic probes in optical imaging of tumors", CNST Nanotechnology Workshop, Urbana-Champaign, IL, May 4-5, 2006.
  9. De Leo, G., Wooley, K.L., Hawker, C.J., Fréchet, J.M.J, Welch, M.J., Schuster, D.P, Anderson, C.J.,  "Integrated Nanosystems for Diagnosis and Therapy NHLBI Program of Excellence in Nanotechnology", CNST Nanotechnology Workshop, Urbana-Champaign, IL, May 4-5, 2006.
  10. Wooley, K.L., "The Development of Shell Crosslinked Nanoparticles for Biomedical Applications in vivo", Kodak Emerging Technologies Symposium, Eastman Kodak Company, Rochester, NY, May 12, 2006.
  11. Almutairi, A. and Fréchet, J.M.J "Polymer based nano-systems for combined diagnosis and therapy", 12th International Conference on Polymers and Organic Chemistry, Okazaki, Japan. July 2-7, 2006.
  12. Almutairi, A. Akers, W., Abendschein, D., Berezin, M., Achilefu, S., Fréchet, J.M.J. "Polymer based nano-systems for combined diagnosis and therapy", Gordon Research Conference, Big Sky, Montana, September 3-8, 2006.
  13. Cohen, J. A., Akers, W., Berezin, M., Achilefu, S.A., Fréchet, J.M.J. "Poly(acrylamide)-based microparticles for cardiovascular imaging and therapeutic applications", Fall American Chemical Society Meeting, San Francisco, CA, September 10-14, 2006.
  14. Almutairi, A., Akers, W., Abendschein, D., Berezin, M., Achilefu, S.A., Fréchet, J.M.J. "Dendrimer-polymer based nano-systems for combined diagnosis and therapy", Fall American Chemical Society Meeting, San Francisco, CA, September 10-14, 2006.
  15. Li, Y., Harrisson, S., Wooley, K.L. "Shell Crosslinked Nanoparticles Containing Degradable Crosslinkers for Controlled Drug Delivery", 232nd National American Chemical Society Meeting, San Francisco, CA, September 10-14, 2006.
  16. Oquare, B.Y., Fang, H. and Taylor, J.S. "Design and synthesis of peptide nucleic acid (PNA) FRET and probes and molecular beacons (MBs) or mRNA targeting and direct imaging of gene transcription", Abstracts of Papers, 232nd National American Chemical Society Meeting, San Francisco, CA, United States, Sept. 10-14, 2006, BIOL-106.
  17. Goodwin, E. R., Lee, C. C., Fox, M. E., Fréchet, J.M.J. "Synthetic variability in asymmetric dendrimers for drug delivery", 232nd Fall American Chemical Society Meeting,San Francisco, CA, USA. (Oral Presentation) 2006.
  18. Almutairi, A., Akers, W., Abendschein, D., Berezin, M., Achilefu, S. A., Fréchet, J.M.J., "Dendrimer-polymer based nano-systems for combined diagnosis and therapy", 232nd Fall American Chemical Society Meeting, San Francisco, CA, USA. (Oral Presentation), 2006.
  19. Cohen, J. A., Akers, W., Berezin, M., Achilefu, S. A., Fréchet, J.M.J. "Poly(acrylamide)-based microparticles for cardiovascular imaging and therapeutic applications", 232nd Fall American Chemical Society Meeting, San Francisco, CA, USA. (Poster Presentation), 2006.
  20. R. Rossin, E. Pressly, et al. "Evaluation of 64Cu-radiolabeled nanoparticles for the diagnosis and treatment of disease", 7th International Symposium on Technetium in Chemistry and Nuclear Medicine, Bressanone (BZ) - Italy, Sept. 6-9. (Poster Presentation), 2006.
  21. Wooley, K.L. "Well-defined Nanostructured Materials: Discrete nanoobjects and nanoscopically-resolved crosslinked networks, and study of their unique host behaviors", University of Utah, Department of Chemistry, Salt Lake City, UT, February 2, 2006.
  22. Wooley, K.L. "Well-defined Nanostructured Materials: Discrete nanoobjects and nanoscopically-resolved crosslinked networks, and study of their unique host behaviors", William H. Rauscher Lectureship, Rennselaer Polytechnic Institute, Department of Chemistry, Troy, NY, February 14, 2006.
  23. Wooley, K.L. "Well-defined Nanostructured Materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", Purdue University, Weldon School of Biomedical Engineering, West Lafayette, IN, March 1, 2006.
  24. Wooley, K.L. "Well defined nanostructured materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", New York University, Department of Chemistry, New York, NY, April 14, 2006.
  25. Wooley, K.L. "Well defined nanostructured materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", University of Florida, Department of Chemistry and Center for Macromolecular Science & Engineering, Gainesville, FL, April 20, 2006.
  26. Wooley, K.L. "Well defined nanostructured materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", University of Delaware, Department of Materials Science and Engineering, Newark, DE, May 3, 2006.
  27. Wooley, K.L. "Well defined nanostructured materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks…and study of their unique host behaviors", University of Massachusetts, Department of Chemistry, Amherst, MA, May 11, 2006.
  28. Wooley, K.L. "The Development of Shell Crosslinked Nanoparticles for Biomedical Applications in vivo", Kodak Emerging Technologies Symposium, Eastman Kodak Company, Rochester, NY, May 12, 2006.
  29. Wooley, K.L. "The Syntheses and Studies of Nanoscale Polymer-based Objects Originating from Block Copolymer Self Assembly, Brush Block Copolymer Construction, or Cellulose Nanocrystal Templating", Unilever Research China, Shanghai, China, June 7, 2006.
  30. Wooley, K.L. "Well-defined Nanostructures Facilitated by Living Polymerization and Supramolecular Assembly", Macro Group UK International Conference on Polymer Synthesis, University of Warwick, UK, July 31, 2006.
  31. Wooley, K.L. "The Transformation of Block Copolymers into Discrete Nanoscale Objects and into Bulk Composite Materials that Present Complex Features", Mitsubishi Chemical Corporation Technical Advisory Board on Polymer Nanocomposites, Tokyo, Japan, August 30-September 1, 2006.
  32. Wooley, K.L. "The Development of Shell Crosslinked Nanoparticles for Biomedical Applications in vivo", 2nd International Conference on Bioengineering and Nanotechnology, Santa Barbara, CA, September 5-7, 2006.
  33. Wooley, K.L. "Shaped Core-shell Morphologies Assembled Intramolecularly within Brush Block Copolymers and Intermolecularly between Linear Block Copolymers", 232nd American Chemicial Society National Meeting, San Francisco, CA, September 10, 2006.
  34. Wooley, K.L. "The Development of Shell Crosslinked Nanoparticles for Biomedical Applications in vivo", 232nd American Chemical Society National Meeting, San Francisco, CA, September 10, 2006.
  35. Wooley, K.L. "Well Defined Nanostructured Materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", Indiana University, Department of Chemistry, Bloomington, IN, October 4, 2006.
  36. Wooley, K.L. "Well Defined Nanostructured Materials: Discrete nanoobjects and nanoscopically resolved crosslinked networks", 2006 Xerox Distinguished Lecture Series, Mississauga, ON, Canada, October 20, 2006.
  37. Wooley, K.L. "The Transformation of Block Copolymers into Discrete Nanoscale Objects and into Bulk Composite Materials that Present Complex Features, Each with Consideration of Biomedical Applications", University of Missouri-Kansas City, Department of Chemistry, Kansas City, MO, November 2, 2006.
  38. Wooley, K.L. "The Development of Well-defined Nanoscale Objects for Biomedical Applications (with tissue selective targeting) in vivo", American Heart Association Scientific Sessions 2006, Chicago, IL, November 12, 2006.
  39. Wooley, K.L. "Shell crosslinked block copolymer micelles: Robust nanostructured materials for fundamental studies and applications in nanomedicine", Center for Drug Delivery and Nanomedicine, University of Nebraska Medical Center, College of Pharmacy, Omaha, NE, November 16, 2006.
  40. Wooley, K.L. "The Transformation of Block Copolymers into Bulk Composite Materials that Present Complex Features and into Discrete Nanoscale Objects", Northwestern University, Department of Chemistry, Evanston, IL, November 17, 2006.
  41. Wooley, K.L. "Complex, amphiphilic polymer nanostructures, originating from combinations of living polymerizations, supramolecular assembly and regioselective crosslinking", Columbia University, Department of Chemistry, New York, NY, February 1, 2007.
  42. Wooley, K.L. "The Promise of Nanotechnology in Medicine", Frontiers in Human Pathobiology Seminar Series, Washington University School of Medicine, St. Louis, MO, February 14, 2007.
  43. Wooley, K.L. "Organic Nanostructures with Well-defined Size, Shape, Structure and Properties", University of Illinois, Urbana-Champaign, Chemistry-Biology Interface Seminar, Urbana, IL, March 12, 2007.
  44. Wooley, K.L. "Complex Constructs Having Nanoscale Features by Combining Incompatible Polymer Components", 233rd American Chemical Society National Meeting, Chicago, IL, March 25 2007.
  45. Wooley, K.L. "Nanoparticles and Nanocages Originating from Well-defined Brush Block Copolymers", 233rd American Chemical Society National Meeting, Chicago, IL, March 28, 2007.
  46. Xu, J., Wooley, K. L. "Functionalization of shell crosslinked nanoparticles and their biodistribution assessment", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  47. Venkataraman, S., Wooley, K. L. "Polymerization of di(ethylene glycol) 2-ethyl hexyl ether acrylate via reversible addition-fragmentation chain transfer polymerization", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  48. Venkataraman, S., Wooley, K. L. "Importance of the hydrophobic core of nanostructures prepared from amphiphilic block copolymers to the morphology of calcium carbonate crystals", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  49. Shokeen M., Powell K. T., Anderson, C. J., Wooley, K. L. "Taking the graduate classroom teaching a step further", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  50. Lee, N. S, Ruda, C. M, Li, Y., Wooley, K. L. "Aqueous-only pH induced micelle assembly of poly(acrylic acid)-b-poly(p-hydroxystyrene)", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 27, 2007.
  51. Powell, K.T., Cheng, C., Du, W., Wooley, K.L. "Hyperbranched Fluorobranched (HBFP(III)) Designed as Complex Nanostructures for Potential Imaging and Therapeutic Delivery", 233rd American Chemical Society Meeting, Chicago, IL, USA, March 25-29, 2007.
  52. Almutairi, A., Cohen, J. A., Akers, W., Achilefu, S., Fréchet, J.M.J. "Polymer based nano-systems for combined diagnosis and therapy", Gordon Research Conference, Ventura, CA, USA 2007.
  53. Almutairi, A., Cohen, J. A., Akers, W., Achilefu, S., Fréchet, J.M.J. "Polymer based nano-systems for combined diagnosis and therapy", Gordon Research Conference, Ventura, CA, USA. (Poster Presentation) 2007.
  54. Almutairi, A. 'Designing Nanoscale Delivery Vehicles for Bioactive Agents", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  55. Rossin, R. "Nanotechnology for Imaging and Imaging for Nanotechnology: In vivo evaluation of new radiolabeled stealth nanocarriers", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  56. Taylor, J.S. "PNA-based Agents for Imaging Gene Expression", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  57. Fiamengo, A.L., Shokeen, M., Li, Z., Sun, G., Xu, Z., Pressly, E., Hawker, C., Wooley, K.L. and Anderson, C.J., "Binding affinity determination of RGD-functionalized nanoparticles to αvβ3 and αvβ5 integrins", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  58. Xu, J., Sun, G., Hagooly, A., Rossin, R., Li, Z., Fukukawa, K., Messmore, B., Moore, D., Welch, M.J., Hawker, C. and Wooley, K.L. "Functionalization of Shell Crosslinked Nanoparticles and Their Biodistribution Assessment", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  59. Du, W., Powell, K.T., Zheng, J., Conradi, M., Wooley, K.L. "Unique Nanostructures through PEGylation of Hyperbranched Fluoropolymer (HBFP) Scaffolds", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  60. Li, Y., Nyström, A.M., Wooley, K.L. "Hydrolytically-degradable nanoparticles for drug delivery", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  61. Li, Z., Xu, J., Sun, G., Banerjee, D., Zheng, J., Woodard, P., Moore, D.A. and Wooley, K.L. "Labeling of Shell Crosslinked Nanoparticles (SCKs) for MRI", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  62. Berezin, M., Akers, W., Almutairi, A., Fréchet, J. M.J., Achilefu, S. "Monitoring Biodegradation of Near-Infrared Fluorescent Stealth Nanoparticles by Time-Domain Fluorescence Imaging", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  63. Fan, J and Achilefu, S. "Synthesis and Application of Gold-Nanoparticle-Peptide Conjugates to Detect Protease by Fluorescence Resonance Energy Transfer", Second Annual Nanotechnology & the Life Sciences Symposium, St. Louis, MO, USA, March 30-31, 2007.
  64. Wooley, K.L. "Fundamental Aspects of the Preparation and Study of Discrete Nanoscale Objects, Designed for Biomedical Applications", Phi Lambda Upsilon Lectureship, Kansas State University, Department of Chemistry, Manhattan, Kansas, April 5, 2007.
  65. Wooley, K.L. "Robust nanostructured materials for fundamental studies and applications in nanomedicine", Etter Memorial Lectureship in Chemistry, University of Minnesota, Department of Chemistry, Minneapolis, MN, April 12, 2007.
  66. Wooley, K.L. "Crafting organic nanostructures with well-defined size, shape, structure and properties", Smith College, Department of Chemistry, Northampton, MA, April 26, 2007.
  67. Rossin, R., Zhou, Z., Muro, S., Kozlowski, J., Welch, M.J., Muzykantov, V.R., Schuster, D. "PET imaging of lung endothelium with 64Cu-labeled ICAM-1 targeted nanoparticles", 17th International Symposium on Radiopharmaceutical Sciences in Aachen, Germany, April 30 - May 4, 2007.
  68. Hagooly, A., Pressly, E., Rossin, R., Fukukawa, K., Messmore, B., Hawker, C.J., Welch, M.J. "Novel nanocarriers for imaging and drug delivery: in vivo evaluation of 64Cu-labeled PEG Graft Copolymers", 17th International Symposium on Radiopharmaceutical Sciences in Aachen, Germany, April 30 - May 4, 2007.
  69. Wooley, K.L. "Advancing Synthetic Organic Chemistry Concepts Toward Nanoparticles and Nanocages: Convergent and divergent approaches, originating from well-defined block copolymers and brush block copolymers, respectively", Dow Lecturer in Organic Chemistry, Massachusetts Institute of Technology, Department of Chemistry, Cambridge, MA, May 4, 2007.
  70. Rossin, R., Abendschein, D., Zheng, J., Sharp, T., Woodard, G.E., McQuade, M.J., Welch, M.J., Woodard, P.K. "64Cu-Labeled natriuretic peptide: a promising tracer for atherosclerotic plaque molecular imaging with PET", Oral presentation at the 54th SNM Annual Meeting, June 2-6, 2007, Washington, D.C. (J Nucl Med, 2007, 48 (Suppl. 2), 103P).
  71. Wooley, K.L. "Application of Synthetic Organic Chemistry Concepts and Methodologies Toward the Construction of Nanoscopic Target Molecules", 40th National Organic Chemistry Symposium, Duke University, Durham, North Carolina, June 5, 2007.
  72. Wooley, K.L. "Current Research in Nanotechnology and Its Applications to Medicine", Cornerstone Life Science Connections Program, Washington University, St. Louis, MO, June 25, 2007.
  73. Akers W., Berezin M., Almutairi A., Fréchet J., Achilefu S. "Imaging Molecular Processes by Optical Methods", 34-th annual meeting of Society of Controlled Release Society, Long Beach, CA, July 7-11, 2007.
  74. Wooley, K.L. "The Transformation of Block Copolymers into Bulk Composite Materials that Present Complex Features and into Discrete Nanoscale Objects", Milliken Research Corporation, Spartanburg, SC, August 3, 2007.
  75. Wooley, K.L. "From Dendrimers to Supramolecular and Covalent Nanostructures", 234th American Chemical Society National Meeting, Boston, MA, August 19, 2007.
  76. Fiamengo, A.L., Li, Z., Sun, G. Xu, J., Wooley, K.L., Anderson, C.J. "Binding affinity determination of RGD-functionalized shell crosslinked nanoparticles to αvβ3 and αvβ5 integrins", 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  77. Oquare, B.Y., Fang, H., Taylor, J.-S. "Peptide nucleic acide (PNA) FRET agents for imaging gene expression", Abstracts of Papers, 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007, MEDI-104.
  78. Fang, H., Oquare, B.Y., Zhang, Y., Taylor, J.-S. "Antisense cassette for gene expression imaging", Abstracts of Papers, 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007, BIOL-168.
  79. Powell, K.T., Anderson, C.J., Wooley, K.L. "Probing the Effect of Visual and Kinesthetic Teaching Methodologies on Middle School Science Students", 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  80. Li, Y.; Du, W.; Sun, G.; Wooley, K.L. "Preparation of Shell Crosslinked Nanoparticles Containing pH Sensitive Crosslinkers for Drug Delivery", PMSE, 234th American Chemical Society National Meeting, Boston, MA, August 19-23, 2007.
  81. Almutairi, A., Rossin, R., Shokeen, M., Berezin, M., Akers, W., Guillaudeu, S., Anderson, C., Achilefu, S., Welch, M.J., Fréchet, J.M.J 'Nanomaterials for biomedical imaging', American Chemical Society-Academic Employment Initiative Fall National Meeting, Boston, MA, USA, August 2007.
  82. Almutairi, A., Rossin, R., Shokeen, M., Berezin, M., Akers, W., Guillaudeu, S., Anderson, C., Achilefu, S., Welch, M.J., Fréchet, J.M.J, "Designing nanoscale carriers for bioactive agents", American Chemical Society-Academic Employment Initiative Fall National Meeting, Boston, MA, USA, August 2007.
  83. Li, Y.; Du, W.; Sun, G. and Wooley, K. L. "Preparation of Shell Crosslinked Nanoparticles Containing pH Sensitive Crosslinkers for Drug Delivery", 234th Meeting of the American Chemical Society, Boston, MA, August, 2007.
  84. Shokeen, M.1, Fiamengo, A.L.1, Rossin, R.1, Pressly, E.D.2, Fukukawa, A.2, Almutairi, A.3, Welch, M.J.1, Hawker, C.J.2, Fréchet, J.M.J.3, Anderson, C.J.1, 1Department of Radiology, Washington University School of Medicine, Saint Louis, USA; 2Materials Research Lab, University of California, Santa Barbara, CA, USA; 3Department of Chemistry, University of California, Berkeley, CA, USA. "Developing Optimized High Throughput Assays for Screening αvβ3 Targeting Nanoparticles for Diagnosis and Therapy", Oral presentation at the Joint Molecular Imaging Conference, Providence, Rhode Island, September 9, 2007.
  85. Wooley, K.L. "The Transformation of Block Copolymers into Bulk Composite Materials that Present Complex Features and into Discrete Nanoscale Objects", 3M ESPE Dental Products, St. Paul, MN, September 18, 2007.
  86. Wooley, K.L. "Synthetic Methodologies for the Preparation of Polymers and Nanoscale Objects", 29th Annual Bayer Lecture Series, University of Pittsburgh, Pittsburgh, PA, November 16, 2007.
  87. Wooley, K.L. "Synthetic Methodologies for the Preparation of Polymers and Nanoscale Objects I", Frontiers in Chemical Research Distinguished Lecture Series, Texas A&M University, College Station, TX, November 26, 2007.
  88. Wooley, K.L. "Synthetic Methodologies for the Preparation of Polymers and Nanoscale Objects II", Frontiers in Chemical Research Distinguished Lecture Series, Texas A&M University, College Station, TX, November 27, 2007.
  89. Wooley, K. L.,"Integration of Syntheses, Physicochemical Characterization, and Biological Testing in vitro and in vivo to Address Significant Medical Needs", Frontiers in Chemical Research Distinguished Lecture Series, Texas A&M University, College Station, TX, November 28, 2007.
  90. Wooley, K. L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology", Society of Professors Emeriti, Washington University, St. Louis, MO, January 14, 2008.
  91. Berezin, M.K., Lee, H., Akers, W., Nikiforovich, G., and Achilefu, S., "Fluorescent lifetime of near infrared dyes for structural analysis of serum albumin", SPIE—The International Society for Optical Engineering, San Jose, CA, January 22, 2008.
  92. Berezin, M.K., Almutairi, A., Guillaudeu, S.J., Nikiforovich, G., Akers, W., Achilefu, S., and Fréchet, J.M.J., "Activatable biodegradable nanoprobes for NIR fluorescence intensity & lifetime imaging", Siteman Center of Cancer Nanotechnology Excellence-Program of Excellence in Nanotechnology (SCCNE-PEN) Seminar, St. Louis, MO, February 2, 2008.
  93. Wooley, K.L. "Synthetic Methods for the Preparation of Well-defined Nanostructures, Designed as Versatile Scaffolds for Imaging and Therapy of Acute Vascular Injury, Cancer, and other Targets", Institute for Environmental Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, February 8, 2008.
  94. Shokeen M., "Targeted Nanoparticles for Diagnosis and Therapy", 4th Annual Postdoc Scientific Symposium, Washington University School of Medicine, February 26, 2008. Invited Talk
  95. Wooley, K. L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology", University of California-Irvine, Department of Nanotechnology, Irvine, CA, March 12, 2008.
  96. Lee, N.S., Neumann, W.L., Freskos, J.N., Marzan, T.A., Shieh, J.J., Dorshow, R.B., Wooley, K.L., "Photonic shell-crosslinked nanoparticle probes for optical imaging and monitoring", Biomedical Optics Topical Meeting in Optical Society of America, St. Petersburg, FL, March 16, 2008.
  97. Powell, K.T., Du, W., Anderson, C.J., Wooley, K.L.  "Scientific Leadership:  The true purpose of the academy", March 15, 2008, Southern Illinois University Edwardsville, East Saint Louis Education Center, Saint Louis, MO.
  98. Nyström, A. M., Wooley, K.L. "Tuning the crystalline melting point of shell crosslinked nanoparticles", American Chemical Society, Division of Polymer Chemistry, New Orleans, LA, April 2008, Polymer Preprints 2008, 49(1), 1097-1098.
  99. Nyström, A. M., Xu, J., Wooley, K.L. "Uptake and release of therapeutic agents from shell-crosslinked nanoparticles", Meeting of the American Chemical Society, New Orleans, LA, PMSE Preprints, April 2008.
  100. Wooley, K. L., "Shell Crosslinked Knedel-like (SCK) Nanoparticles and Hyperbranched Fluoropolymers (HBFP)", Johns Hopkins University, Department of Chemistry, Baltimore, MD, April 1, 2008.
  101. Lee, N.S., Neumann, W.L., Freskos, J.N., Marzan, T.A., Shieh, J.J., Dorshow, R.B., Wooley, K.L., "Photonic shell-crosslinked nanoparticle probes for optical imaging and monitoring", 235th American Chemical Society National Meeting, New Orleans, LA, April 10, 2008.
  102. Wooley, K. L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology", Central Michigan University, Mt. Pleasant, MI, April 23, 2008.
  103. Wooley, K. L. "What is Nano and Why is it Important?", Nanofuture:  You and the Environment Series, Saint Louis Science Center and the Academy of Science of St. Louis, St. Louis, MO, May 6, 2008.
  104. Achilefu, S.  "Nanomolecules and Nanoparticles in Optical Imaging of Tumors", Nanotechnology Seminar Series by the Center for Nano Technology, May 5-7, 2008, Center for Nanotechnology, University of Washington, Seattle, WA.
  105. McCommis, K.S., Rossin, R., Abendschein, D.R., Ochoa, B., Woodard, G.E., Welch, M.J., Woodard, P.K., Zheng, J.  "Detection of Atherosclerotic Plaque Progression:  Correlation of Contrast MRI with PET using 64Cu-labeled Natriuretic Peptide".  Proceedings of the International Society for Magnetic Resonance in Medicine, p.99, #519, May 7, 2008, Toronto.
  106. Anderson, C.J., Welch, M.J.  "Graduate training in imaging sciences at Washington University", invited presentation at the American Nuclear Society Annual Meeting, Anaheim, CA, June 11, 2008. 
  107. Liu, Y., Hagooly, A., Sun, G., Rossin, R., Xu, J., Nyström, A. M., Li, Z., Wooley, K. L. and Welch, M. J., "In vivo evaluation of 64Cu labeled PEGylated shell crosslinked nanoparticles (SCKs) as candidates for imaging and drug delivery", Oral presentation at the 55th SNM Annual Meeting, June 14-18, 2008, New Orleans, LA., (J. Nucl Med, 2008, 49(Suppl.1), 44P, 174).
  108. Achilefu, S., Akers, W., "Applications of Optical Imaging", National Cancer Institute 2008 Cancer Research Imaging Camp, June 15-20, 2008, Duke University, Durham, NC.
  109. Wooley, K. L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology:  With an emphasis on devices for nanomedicine", Rhodia, Inc., Bristol, PA, June 23, 2008.
  110. Nyström, A. M., Wooley, K.L.  "Tuning the Release of Active Components from Nanoparticles by Defining the Crystallinity of the Particle Core", 2008 Intn'l. Conf on Nanotechnology for the Forest Products, St. Louis, MO, June 25, 2008.
  111. Wooley, K.L., "Functional Nanostructures via a Combination of Strategies Involving Functionalized Polymers and Postassembly Manipulations", the 42nd World Polymer Congress (Macro 2008), Polymers at Frontiers of Science and Technology, Taipei, Taiwan, June 30, 2008.
  112. Achilefu, S., "Hidden treasures of invisible light-Harnessing the power of light for imaging and treating diseases", Biomed RAP Lecture, July 15th, 2008, Washington University School of Medicine, St. Louis, MO.
  113. Achilefu, S., et al, "Fluorescence lifetime imaging in vivo", Gordon Research Conference, Lasers in Medicine & Biology, July 20-25, 2008, Holderness School, Holderness, NJ.
  114. Wooley, K.L., "“Polymer Chemistry as Applied to the Emerging Field of Nanotechnology: With an emphasis on devices for nanomedicine", Prague Meetings on Macromolecules, 48th Microsymposium, Prague, Czech Republic, July 22, 2008.
  115. Achilefu, S., et al, "Fluorescence lifetime imaging of tumors using near infrared fluorescent molecular probes", 236th ACS National Meeting & Exposition, August 17-21, 2008, Philadelphia, PA.
  116. Achilefu, S., et al, "Chemical and biochemical contrast strategies for optical imaging of molecular processes in vivo", 236th ACS National Meeting & Exposition, August 17-21, 2008, Philadelphia, PA.
  117. Wooley, K.L., "Advances with Regioselective Functionalization of Core-shell Nanostructures: Taking advantage of living polymerizations of functional monomers and efficient, orthogonal chemistries", 236th American Chemical Society National Meeting, Philadelphia, PA, August 18, 2008.
  118. Anderson, C.J., Welch, M.J.  "Graduate training in imaging sciences at Washington University", invited presentation, American Chemical Society Fall Meeting, Philadelphia, PA, August 19, 2008. 
  119. Fiamengo, A. L., Ye, Y., Achilefu, S., Anderson, C.J.  "Binding affinity and cellular internalization of αvβ3 targeting ligands for molecular imaging of cancer and cardiovascular disease", Oral presentation, American Chemical Society Fall Meeting, Philadelphia, PA, August 19, 2008.
  120. Fan, J., Berezin, M, Akers, W., Basak, S., Biswas P., Achilefu S., “Tantalum Oxide Nanoparticles, a Novel Computed Tomography (CT) Contrast Agent”; 1st Annual Radiological Sciences Research Day, September 4, 2008.
  121. Wooley, K.L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology: An emphasis on devices for nanomedicine", Illinois Wesleyan University, Natural Science Colloquium, Bloomington, IL, September 12, 2008.
  122. Wooley, K.L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology: An emphasis on devices for nanomedicine", Haverford College, Haverford, PA, September 19, 2008.
  123. Wooley, K.L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology: An emphasis on devices for nanomedicine", 2008 BMES Annual Fall Meeting, St. Louis, MO, October 3, 2008.
  124. Wooley, K.L., "The Application of Synthetic Organic Chemistry Concepts toward the Preparation of Well-defined Nanostructures, and Their Transformation into Functional Devices for Nanomedicine", Wayne State University, Frontiers in Chemistry Seminar, Detroit, MI, October 27, 2008.
  125. Wooley, K.L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology: An emphasis on devices for nanomedicine", University of Connecticut, Polymer Program of the Institute of Materials Science, Storrs, CT, November 7, 2008. 
  126. Wooley, K.L., "Polymer Chemistry as Applied to the Emerging Field of Nanotechnology: An emphasis on devices for nanomedicine", University of Georgia, Department of Chemistry, Athens, GA, November 18, 2008.
  127. Wooley, K.L., "Intricacies with Synthetic Methodology and Nanoparticle Structure in Designing Nanostructured Materials for in vivo Imaging and Therapeutic Delivery", Kanagawa University, Symposium on Creation of Nano-Space from Polymer, Yokohama, Japan, December 18, 2008.
  128. Wooley, K.L., "Targeted Delivery Nano-devices for Imaging Probes", 24th Transatlantic Airway Conference: Imaging pulmonary pathology and target molecular signature, Lucerne, Switzerland, January 22, 2009.
  129. Akers, W. J., Berezin, M. Y., Lee, H., Achilefu, S.I., "In vivo imaging with near-infrared fluoresencee lifetime contrast", SPIE- The International Society for Optical Engineering, San Jose, CA, January 24-29, 2009.
  130. Liu, Y., Rossin, R., Abendschein, D. R., Zheng, J., Woodard, G. E., McCommis, K., Woodard, P. K., Welch, M. J., "Molecular Imaging of Atherosclerotic Plaque with 64Cu-Labeled Natriuretic Peptide and Positron Emission Tomography", Washington University Postdoc Symposium, February 24, 2009.
  131. Pressly, E.D., Hawker, C.J., "Nanoparticles for targeted PET imaging", ACS Spring National Meeting, Salt Lake City, UT, March 2009.
  132. Cauet Solene I., Lee Nam S. and Wooley Karen L. "Multiple stages toward "green" production of complex nanoscale objects." 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26, 2009.
  133. Wooley, K. L., "Multistage Hierarchical Assembly of Polymers and Nanostructures to Afford Well-defined, Stimulus-responsive and/or Reactive Nanostructures", 237th American Chemical Society National Meeting, Salt Lake City, Utah, March 23, 2009.
  134. Wooley, K. L., "Complex Nanoscale Objects as Diverse Carrier Systems for Broad Applications in Nanomedicine", 237th American Chemical Society National Meeting, Salt Lake City, Utah, March 24, 2009.
  135. Lee, N.S., Sun, G., Lin, Y., Neumann, W.L., Freskos, J.N., Shieh, J.J., Dorshow, R.B., Wooley, K.L.,  "Photonic, pH-responsive shell-crosslinked nanoparticle probes for optical imaging and monitoring," 237th American Chemical Society National Meeting, Salt Lake City, UT, March 26, 2009.
  136. Anderson, C.J., Sobotka, L.G., "Nuclear and radiochemistry at Washington University in St. Louis", MARC VIII Conference, Kona, HI, April 5-10, 2009.
  137. Shrestha, R., Nyström, A. M., Wooley, K.L., "Investigating the Effects of Sizes and Morphologies of Thermoresponsive Shell Crosslinked Nanoparticles in Targeting." 22nd Annual Organic Chemistry Symposium, University of Missouri-Columbia, Columbia, MO. April 18th, 2009, (Poster Presentation).
  138. Wooley, K. L., "Overview of Targeted Nanoparticles for Imaging", Symposium on Multimodality Cardiovascular Molecular Imaging, SNM Molecular Imaging Center of Excellence, Bethesda, MD, April 30, 2009.
  139. Liu, Y., Rossin, R., Abendschein, D.R., Zheng, J.; McCommis, K.S.; Woodard, G.E.; Woodard, P.K.; Welch, M.J.; "Molecular Imaging of Atherosclerotic Plaque with 64Cu-Labeled Natriuretic Peptide and Positron Emission Tomography", Symposium on Multimodality Cardiovascular Molecular Imaging, National Institutes of Health, Bethesda, MD, April 30 - May 1, 2009.
  140. Liu, Y., Ibricevic-Richardson, A., Gunsten, S., Cohen, J.L., Kozlowski, J., Fréchet, J.M.J.; Walter, M.J., Welch, M.J., Brody, S.L., 2009 American Thoracic Society International Conference, San Diego, CA, poster presentation, May 15-20, 2009.
  141. Lee, N.S., Sun, G., Lin, Y., Neumann, W.L., Freskos, J.N., Shieh, J.J., Dorshow, R.B., Wooley, K.L.  "pH-Sensing, optically active nanodevices:  Part I. Spherical vs. rod-shaped morphologies," Covidien/Washington University Nanotechnology Symposium, Covidien Imaging Solutions R&D, May 20, 2009.
  142. Lin, Y., Lee, N. S.,　Nyström, A. M., Neumann, W. L., Freskos, J. N., Shieh, J. J., Berberich, D. W, Dorshow, R. B.　"Nanodevices Designed for Loading and Release of Pharmaceutically-active Agents and Their Transdermal Delivery"　Covidien/Washington University Nanotechnology Symposium, Covidien Imaging Solutions R&D, May 20, 2009.
  143. Shrestha, R., Nyström, A. M., Wooley, K.L., "Investigation of Thermal Properties of Shell Crosslinked Knedel-like Nanoparticles." Gordon Research Conference, Mount Holyoke College, South Hadley, MA. June 20th, 2009, (Poster Presentation).
  144. Lin, Y.(Lily), Wooley, K.L., "Nanodevices Designed for Loading and Release of Pharmaceutically-active Agents and Their Targeted Delivery", 2009 Polymers Gordon Research Conference, Mt. Holyoke College, South Hadley, MA, June 25, 2009.
  145. Wooley, K.L., "Strategic Design of Polymers as Well-defined Materials for Nanomedicine", 2009 Polymers Gordon Research Conference, Mt. Holyoke College, South Hadley, MA, June 25, 2009.
  146. Liu, Y., Abendschein, D.R., Woodard, G.E., Woodard, P.K., Welch, M.J.,  18th International Symposium of Radiopharmaceutical Sciences, July 12-17, 2009, Edmonton, Canada.
  147. Glaus, C., Hagooly, H., Welch, M.J., Bao, G., "Dual-modality Nanoparticles for PET/MR Molecular Imaging" 18th International Symposium of Radiopharmaceutical Sciences, Edmonton, Canada. (Oral Presentation). July 12-17, 2009.
  148. Fiamengo, A.L., Ye, Y., Achilefu, S., Anderson, C.J., "In vitro and in vivo evaluation of structurally diverse Cu64-labeled RGD peptides for PET imaging of αvb3 expression." 18th International Symposium of Radiopharmaceutical Sciences, July 12-17, 2009, Edmonton, Canada. (oral presentation).
  149. Wooley, K.L., "Synthetic Methodologies for the Preparation of Functional Macromolecules and Nanostructures", 238th American Chemical Society National Meeting, Washington, DC, August 18, 2009; Award address for receipt of the 2009 Herman F. Mark Scholar Award, from the American Chemical Society Division of Polymer Chemistry, sponsored by Elsevier.
  150. Berezin, M.Y., "Engineering NIR Dyes for Fluorescent Lifetime Contrast, EMBC, Minneapolis, MN, September 2-6, 2009.
  151. Liu, Y., Abendschein, D.R., Woodard, G.E., Zheng, J., McCommis, K., Woodard, P.K., Welch, M.J. "Assessment of Natriuretic Peptide Clearance Receptor with Positron Emission Tomography in Cardiovascular disease models", Computers in Cardiology, September 13-16, Park City, Utah, 2009.
  152. Cauet, S. I., Lee, N. S., Wooley, K. L. "PEGylated block copolymers via direct RAFT homo- and copolymerization of acrylic acid and their pH-induced nanoassembly." 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009.
  153. McCommis, K. S., Liu, Y., Abendschein, D. R., Woodard, G. E., Rossin, Gropler, R.J., Zheng, J., Welch, M.J., Woodard, P.K., "Extracellular Matrix Deposition and Natriuretic Peptide Receptor-C Expression in Restenosis after Angioplasty: A MRI and PET Imaging Study in Rabbits", North American Society for Cardiovascular Imaging", 37th Annual Meeting, Orlando, Florida, October 2-6, 2009.
  154. Amir, R. J., Zhong, S., Pochan, D. J., Hawker, C. J. "Enzymatically Triggered Self-Assembly of Block Copolymers", 11th Pacific Polymer Conference, Cairns, Australia, 2009.
  155. Akers, W. J.1, Berezin, M. Y.1, Lee, H.1, Guo, K.1, Almutairi, A.2, Fréchet, J. M. J.3, Fischer, G. M.4, Daltrozzo, E.4, Achilefu, S.I.1,5, "Biological Applications of Fluorescence Lifetime Imaging Beyond Microscopy", SPIE Bios 2010, San Francisco, CA, January 27, 2010.
  156. Berezin, M. Y., Akers, W. J., Lee, H., Guo, K., Almutairi, A., Fréchet J. M. J., Achilefu, S. I. "Strategy for developing pH sensitive NIR probes" SPIE—The International Society for Optical Engineering, San-Francisco, CA, January 23-28, 2010.
  157. Guo, G., Berezin, M.Y., Zheng, J., Akers, W.J., Lin, F., Teng, B., Vasalatiy, O., Gandjbakhche, A., Griffiths, G. L., Achilefu, S. I. "Dual near-infrared optical/MRI organic probe sensitive to protein binding", SPIE—The International Society for Optical Engineering,　 San Francisco, CA, January 23-28, 2010.
  158. Wooley, K.L., "Increasing the Complexity of Materials by Designing Polymer Nanostructures for Hierarchical Assembly", Materials Research Outreach Program Symposium, Santa Barbara, CA, February 3, 2010.
  159. Wooley, K.L., "Strategic Design of Polymers as Well-defined Materials for Nanomedicine", St. Louis Institute for Nanomedicine Symposium, St. Louis, MO, February 13, 2010.
  160. Wooley, K.L., "Strategic Design of Polymers as Well-defined Materials for Nanomedicine", Texas A&M University Biomaterials Day, College, Station, TX, February 22, 2010.
  161. Liu, Y., Pressly, E.D., Abendschein, D.R., Woodard, G., Hawker, C.J., Woodard, P.K., Welch, M.J., "Comparison of Nanoprobe to Peptide Alone Radiotracer for In Vivo Targeted Imaging with Positron Emission Tomography", Washington University 6th Annual Postdoc Scientific Symposium, St. Louis, MO, February 25, 2010.
  162. Wooley, K.L., "Combinations of Polymerization Strategies to Afford Functional Polymers and Regioselectively-functionalized Nanoscopic Objects:  Complex materials from assembly", Virginia Tech, Chevron-Phillips Chemical Company-sponsored Lecture, March 3, 2010.
  163. Cohen, J.L., Hornig, s., Cohen, J.A., Fréchet, J.M.J., "Acetal-modified dextran particles for siRNA delivery", 239th American Chemical Society National Meeting, San Francisco, CA, March 21-25, 2010.
  164. Shrestha, R., Shen, Y., Ibricevic, A., Nyström, A. M., Lin, L., Zhang, Z., Taylor, J-S. A., Brody, S. L., Wooley, K. L. “Shell Crosslinked Nanoparticles for the Delivery of Peptide Nucleic Acids (PNAs) as Imaging Agents for iNOS Expression”, 239th ACS National Meeting, San Francisco, CA March 21st - 25th, 2010.
  165. Wooley, K.L., "Increasing the Complexity of Materials by Designing Polymer Nanostructures for Hierarchical Assembly:  Increasingly-complex nanostructured materials from increasingly-sophisticated macromolecular building blocks", ACS National Meeting, San Francisco, CA, March 23, 2010.
  166. Pressly, E.D., "Functional comb copolymers for medical imaging contrast agents", American Chemical Society Spring National Meeting,  San Francisco, CA, March 23,2010. (Oral)
  167. Wooley, K.L., "Diverse Opportunities—From Materials to Medicine—For Well-defined Polymer Chemistry", Texas A&M University College of Science External Advisory and Development Council Meeting, College Station, TX, March 25, 2010.
  168. Shrestha, R., Nyström, A. M., Wooley, K. L. "Thermally Triggered Shape Deformation and Retention of Shell Crosslinked Nanoparticles", Polymer Technology Industrial Consortium, College Station, TX, April 8th-9th, 2010.
  169. Nothdurft, R., Berezin, M.Y., Achilefu, S.I., Culver, J. P. "Diffuse Optical Tomography of Heterogeneous Fluorophore Lifetimes", Optical Society of America, Biomedical Optics (BIOMED) - Miami, FL April 11-14, 2010.
  170. Wooley, K.L., "Combinations of Polymerization Strategies, to Afford Functional Polymers and Regioselectively-functionalized Nanoscopic Objects", 12th Dresden Polymer Discussion, Meiβen Germany, April 19, 2010.
  171. Brody, Steven L., "Nanoparticles for Lung Imaging and Therapy: Fates and Behaviors", Pulmonary Medicine - Chemical Engineering Research Group Seminar, Keck School of Medicine, University of Southern California, Los Angeles, CA, May 7, 2010.
  172. Liu, Y., Pressly, E.D., Abendschein, D.R., Glaus, C.R., Woodard, G., Hawker, C.J., Woodard, P.K., Welch, M.J., "Comparison of A Cu-64 Labeled Peptide (CANF) with Nanoparticle Agent in A Murine Hind Limb Ischemia Model", 56th SNM Annual Meeting, Salt Lake City, Utah, United States, June 5-9, 2010.
  173. Shrestha, R., Shen, Y. Taylor, J-S. A., Wooley, K. L. "Design and Synthesis of Complex Nanomaterials for Site-Specific targeting", 8th National Graduate Research Polymer Conference, Chapel Hill, NC, June 6th - 9th, 2010.
  174. Cohen, J.L., Hornig, S., Wich, P.R., Cui, L., Cohen, J.A., Fréchet, J.M.J., “Acetal-modified dextran particles for siRNA delivery.”  Gordon Research Conference, Waterville Valley, NH, August 15-20, 2010.
  175. Wooley, K.L., “Well-defined, biologically inspired nanoscopic objects derived from synthetic polymer building blocks”, 3rd International NanoBio Conference, Zurich, Switzerland, August 26, 2010.
  176. Wich, P.R., Cohen J.L., Hornig S., Cohen J. A., Fréchet, J.M.J, “Acetal-modified Dextran Particles for siRNA Delivery”, 3rd EuCheMS Chemistry Congress, Nürnberg, Germany, Aug 29 - Sep 02, 2010.
  177. Wooley, K.L., "Combinations of Polymerization Strategies to Afford Functional Polymers and Regioselectively-functionalized Nanoscopic Objects", Unilever Global, Shanghai, China, September 8, 2010.
  178. Wooley, K.L., "Nanoscopic Polymer Objects of Unique Shapes and Morphologies and Well-defined Structures and Dimensions as Controlled Drug Delivery Devices", Symposium on Innovative Polymers for Controlled Delivery, Suzhou, China, September 15, 2010.
  179. Wooley, K.L., “Sophisticated Plastics: Diverse opportunities – from materials to medicine – for well-defined polymer chemistry”, Indiana State University, Department of Chemistry and Physics, Terre Haute, IA, September 21, 2010.
  180. Liu, Y., Connal, L.A., Pressly, E.D., Abendschein, D.R., Woodard, G., Hawker, C.J., Woodard, P.K., Welch, M.J., "Molecular Imaging of Natriuretic Peptide Clearance Receptor in Atherosclerosis Model with C-atrial Natriuretic Factor Conjugated Nanoprobe", North American Society for Cardiovascular Imaging, 38th Annual Meeting, Seattle, Washington, October, 3-5, 2010.
  181. Wooley, K.L., "Retrosynthetic Analyses of Increasingly Complex Macromolecular Structures", 7th Butler Lectureship Series (a series of ten lectures), Center for Macromolecular Science & Engineering, University of Florida, Gainesville, FL, October 2010.
  182. Wooley, K.L., "Sophisticated Plastics: Diverse opportunities – from materials to medicine – for well-defined polymer chemistry", Texas A&M University Society of Plastic Engineers, Texas A&M University, College Station, TX, November 1, 2010.
  183. Wooley, K.L., "Hierarchical construction of increasingly complex, functional nanostructures", University of Texas, Department of Chemistry and Biochemistry, Austin, TX, November 5, 2010.
  184. Wooley, K.L., "Complex macromolecular and nanoscale structures by combinations of living radical and ring opening polymerizations", 2010 Adlrich Symposium in Materials Science, University of Michigan, Ann Arbor, MI, November 8, 2010.
  185. Wooley, K.L., "Well-defined, biologically inspired nanoscopic objects derived from synthetic polymer building blocks", University of Texas at Dallas, Department of Chemistry, Richardson, TX, November 12, 2010.
  186. Wich, P.R., Fréchet, J.M.J, "Polymeric Particle Systems for the Delivery of Biotherapeutics", ZING Polymer Chemistry Conference, Puerto Morelos, Mexico, Nov 19-22, 2010.
  187. Wooley, K.L., "Combinations of Polymerization Strategies and Self Assembly Processes to Afford Functional Polymers and Regioselectively-functionalized Nanoscopic Objects:  Complex materials from hierarchical assembly", PacifiChem 2010, Honolulu, HI, December 15, 2010.
  188. Liu, Y., Connal, L.A., Pressly, E.D., Abendschein, D.R., Woodard, G., Hawker, C.J., Woodard, P.K., Welch, M.J., "PET Imaging of Natriuretic Peptide Clearance Receptor with 64Cu-labeled Nanoprobe in Cardiovascular Models", Pacifichem 2010, Honolulu, Hawaii, December 15-20, 2010.

Patents

  1. Wooley, K. L., "Cell-permeable Nanoconjugates of Shell-crosslinked Knedel (SCK) and Peptide Nucleic Acids ("PNAs") with mRNA-targeting Sequences for Early Diagnosis and Therapy of Cancer", PCT Int. Appl. 2006, WO 2006044716.
  2. Neumann, W. L., Rajagopalan, R. Dorshow, R. B., Shieh, J. J., Freskos, J., N., Lee, N. S., Wooley, K. L., “Photonic shell-core crosslinked and functionalized nanostructures for biological imaging, anatomical visualization, physiological monitoring and phototherapy,” US Provisional Patent #60/986,171, filed Nov. 7, 2007.
  3. Fredrickson; Glenn H.; (Santa Barbara, CA) ; Kramer; Edward J.; (Santa Barbara, CA) ; Kim; Bumjoon; (Goleta, CA); Hawker; Craig J.; (Montecito, CA), "Method for producing bi-continuous and high internal phase nanostructures"; United States Patent Application 20080001116, Kind Code A1, Fredrickson; Glenn H. ;   et al. January 3, 2008.
  4. Hawker; C.J.; (Santa Barbara, CA) ; Stucky; Galen; (Santa Barbara, CA) ; An; Zesheng; (Goleta, CA); "One-step Microwave Preparation of well-defined and functionalized Polymeric Nanoparticles"; United States Patent Application 20080009558, Kind Code A1, Hawker, C.J.;   et al. January 10, 2008.
  5. Woodard, P.K., Rossin, R., Woodard, G., Welch, M.J., "Natriuretic peptide-mediated imaging of artherosclerotic plaque", US Patent 12/454810, filed June 2009.
  6. Wooley, Karen L.; Dorshow, Richard B.; Freskos, John N.; Neumann, William L.; Shieh, Jeng J.; Lee, Nam S.; Lin, Yun; Sun, Guorong;., "Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH", US Provisional Patent #010739, filed May 14, 2010.
  7. Woodard, P.K., Liu, Y., Pressly, E.D., Hawker, C.J., Abendschein, D.R., Welch, M.J.,  US Provisional Application 61/351,847 entitled “Targeting NPR-C in Angiogenesis with a C-type Natriuretic Factor (CANF)-Comb  Nanocomplex”, was filed June 4, 2010.