Principal
Investigator

Michael J. Welch
Wash Univ - Med

Co-Principal Investigator
Karen L. Wooley
Texas A&M

Program Official
Denis B. Buxton
NHLBI

-- PROJECTS --
Project 1
Karen L. Wooley

Project 2
Carolyn L. Cannon

Project 3
Steven L. Brody

Project 4
Pamela K. Woodard

Dev Proj 1
Michael J. Welch

Dev Proj 2
Mikhail Y. Berezin

Core-PROD
Craig J. Hawker

Core-SKILLS
Joseph P. Culver

Seminar, July 14
Omid Farokhzad,MD
Farrell Holden Audit.
2:00- 3:00 p.m.
Omid C. Farokhzad, M.D.


Press Release
New PEN announced

Monthly Meetings
CSRB Conf Room #4402 at WUSM

PEN Admin Center (ACPEN website)
Click here to learn about the 4 PENs
Inter-PEN website

Michael J. Welch, Ph.D.Welch Group

Michael J. Welch, Ph.D.

Projects 2, 3, and 4
Developmental Project 1 - Nanoagents for chemokine receptor imaging in athersclerosis & acute vascular injury.

Division of Radiological Sciences
School of Medicine, Box 8225
Washington University in Saint Louis
510 South Kingshighway Blvd.
St. Louis, MO 63110-4899
phone: +1 314 362-8435
fax: +1 314 362-8399

Current PEN Initial PEN

 

Goals for the Current PEN Contract

Michael J. Welch is the project leader for Developmental Project 1. He is also involved with Projects 2, 3, and 4.

Facilities

The Division of Radiological Sciences has 14 research laboratories comprising 3,225 square feet. The laboratories are equipped for synthesis and evaluation of radioactive and non-radioactive compounds. Specific equipment includes a cell culture suite, several HPLC and FPLC systems, a LC-Mass Spectrometer, radio-TLC scanners, radioactivity dose calibrators, two autoradiography devices, gamma and beta counters, etc.

The small animal imaging facility is built around State-of-the-Art small animal imaging technology. This technology is housed in newly refurbished laboratory space specifically designed for the non-invasive delineation of disease in rodent models. The facility includes animal housing, physiologic support and monitoring equipment, surgical procedure rooms, and data analysis and archival systems. The imaging equipment includes two Concorde MicroSystem microPET-FOCUS, one microPET-R4, and one ImTek microCAT II System.

Small animal imaging facility
Small animal imaging facility

The radiotracers for imaging studies are produced in the Washington University Medical Center Cyclotron Facility, which includes three cyclotrons, several shielded hot cells and a laminar flow hot cell, GC and HPLC systems for quality control and other equipment for the production of PET radiopharmaceuticals.

These facilities are supported by research grants from the National Institute of Health, the National Cancer Institute, and the Department of Energy.

People

Michael J. Welch, Ph.D.
Co-Investigator and Imaging Component Leader
Division of Radiological Sciences
Washington University School of Medicine
phone: +1 314 362-8436
fax: +1 314 362-8399
welchm@wustl.edu

Eileen A. Cler, B.S.
Program Coordinator
Division of Radiological Sciences
Washington University School of Medicine
phone: +1 314 362-
fax: +1 314 362-
eacler@wustl.edu

Kathleen J. Grapperhaus
Research Technician II
Division of Radiological Sciences
Washington University School of Medicine
phone: +1 314 362-3928
fax: +1 314 362-3911

Suellen C. Greco
Asst Dir Diag Serv Animal Aff
Division of Radiological Sciences
Washington University School of Medicine
phone: +1 314 362-3125
fax: +1 314 362-6480
sue@wustl.edu

Richard Laforest, Ph.D.
Associate Professor of Radiology
Division of Radiological Sciences
Washington University School of Medicine
phone: +1 314 362-8423
fax: +1 314 362-5428
laforestr@wustl.edu

Yongjian Liu, Ph.D.
Postdoctoral Research Associate
Division of Radiological Sciences
Washington University School of Medicine
Phone: +1 314 362-8431
Fax: +1 314 362-8399
liuyo@mir.wustl.edu

Suzanne E. Lapi, Ph.D.
Co-Investigator
Assistant Professor of Radiology
Washington University School of Medicine
phone:  +1 314 362-8435
pax: +1 314 362-5026
lapis@wustl.edu

Sally J. Schwarz, M.S.
Research Associate Professor of Radiology
Washington University School of Medicine
phone:  +1 314 362-8426
fax: +1 314 362-9940
schwarzs@wustl.edu

Kooresh I. Shoghi, Ph.D.
Assistant Professor of Radiology
Washington University School of Medicine
phone:  +1 314 362-8990
shoghik@wustl.edu